Almalik Alaa Mahmoud Ali, Guy Reeves R, Azrag Rasha Siddig
Vector Genetics and Control Laboratory, Department of Zoology, Faculty of Science, University of Khartoum, Sudan.
Max Planck Institute for Evolutionary Biology, Plön Germany.
R Soc Open Sci. 2021 Feb 10;8(2):200980. doi: 10.1098/rsos.200980.
Aquatain mosquito formulation (AMF) is a surfactant that spreads across the surface of water bodies to produce a monomolecular film. This study experimentally evaluates the temporal efficacy of AMF against aquatic stages of and under laboratory conditions. Using the recommended application dose of 1 ml m, a large species-specific difference in the median lethal time for L3-L4 larvae was observed. The median lethal time to 50% mortality (LT50) and 90% mortality (LT90) was 1.3 h, 95% CI [1.2, 1.4] and 3.8 h, 95% CI [3.6, 4.0], respectively, for . The corresponding values for were 8.1 h, 95% CI [7.3, 9.0] and 59.6 h, 95% CI [48.5, 76.2]. Based on data from published laboratory studies for a total of seven mosquito species, drawn from four genera, results in the following three groups, [LT50 = 1-2 h, , ] [LT50 = 8-24, hours, , s.s.] and [LT50 = 72-143 h, , ]. In all experiments, 100% mortality was achieved given sufficient time. The potential relevance of mortality rate estimates, in the context of other studies, on the use of monomolecular films for the control of malaria and arbovirus diseases is discussed.
阿夸坦蚊虫制剂(AMF)是一种表面活性剂,可在水体表面扩散形成单分子膜。本研究在实验室条件下通过实验评估了AMF对[具体蚊虫种类1]和[具体蚊虫种类2]水生阶段的时效作用。使用推荐施用量1毫升/米,观察到L3-L4幼虫的半数致死时间存在较大的种属差异。对于[具体蚊虫种类1],50%死亡率的半数致死时间(LT50)和90%死亡率的半数致死时间(LT90)分别为1.3小时,95%置信区间[1.2, 1.4]和3.8小时,95%置信区间[3.6, 4.0]。[具体蚊虫种类2]的相应值分别为8.1小时,95%置信区间[7.3, 9.0]和59.6小时,95%置信区间[48.5, 76.2]。根据来自四个属的总共七种蚊虫的已发表实验室研究数据,结果分为以下三组,[LT50 = 1 - 2小时,[具体蚊虫种类1],[具体蚊虫种类2]] [LT50 = 8 - 24小时,[具体蚊虫种类3],[具体蚊虫种类4]]和[LT50 = 72 - 143小时,[具体蚊虫种类5],[具体蚊虫种类6]]。在所有实验中,给予足够时间均可实现100%死亡率。本文还讨论了在其他研究背景下,死亡率估计对于使用单分子膜控制疟疾和虫媒病毒疾病的潜在相关性。