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耳炎诺卡菌引起的多发性脑脓肿:病例报告及治疗启示

Multiple Brain Abscesses Due to Nocardia otitidiscaviarum: Case Report and Treatment Implications.

作者信息

Einstein Evan H, Bonda David, Khan Salman, Zlochower Avraham B, D'Amico Randy S

机构信息

Neurosurgery, Lenox Hill Hospital/Donald and Barbara Zucker School of Medicine at Hofstra, New York, USA.

Infectious Disease, Lenox Hill Hospital/Donald and Barbara Zucker School of Medicine at Hofstra, New York, USA.

出版信息

Cureus. 2021 Apr 8;13(4):e14362. doi: 10.7759/cureus.14362.

Abstract

infections typically present in immunocompromised hosts. Brain abscesses caused by species such as and are well-documented in the literature. We present a rare case of an immunocompetent patient with multiple brain abscesses due to requiring a decompressive fronto-temporoparietal craniectomy due to symptomatic intracranial hypertension. The patient was treated with intrathecal amikacin in addition to standard antibiotics with the resolution of the disease and good neurologic outcome. This is one of few case reports overall involving this species within the brain, and the second to report favorable outcomes. This case describes implications for treatment and adds to sparse literature regarding this particular pathogen.

摘要

感染通常发生在免疫功能低下的宿主中。文献中对由[具体物种1]和[具体物种2]等物种引起的脑脓肿有充分记载。我们报告了一例罕见病例,一名免疫功能正常的患者因[具体物种3]患有多发性脑脓肿,由于症状性颅内高压而需要进行减压性额颞顶颅骨切除术。除标准抗生素外,患者还接受了鞘内注射阿米卡星治疗,疾病得到缓解,神经功能预后良好。这是总体上为数不多的涉及该物种在脑内感染的病例报告之一,也是第二例报告有良好预后的病例。本病例描述了治疗方面的影响,并为关于这种特定病原体的稀少文献增添了内容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f5/8105746/c04195d30595/cureus-0013-00000014362-i01.jpg

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