Anderson N B, Lane J D, Monou H, Williams R B, Houseworth S J
Department of Psychiatry, Duke University Medical Center, Durham, N.C. 27710.
Int J Psychophysiol. 1988 Jun;6(2):161-4. doi: 10.1016/0167-8760(88)90047-5.
One hypothesized mechanism for the higher rates and greater severity of essential hypertension among blacks is that this group is particularly susceptible to stress-induced beta-adrenergically mediated cardiovascular hyperreactivity. In this study, we compared the cardiovascular responses to mental arithmetic in 20 white and 17 black, young, normotensive males. Contrary to expectations, the black subjects exhibited significantly smaller changes in heart rate, and systolic and diastolic blood pressure. These findings suggest that cardiovascular reactivity to a mental stressor known to produce beta-adrenergically mediated responses may be lower in some normotensive blacks compared to their white counterparts.
黑人原发性高血压发病率较高且病情较重的一种假设机制是，该群体特别容易受到压力诱导的β-肾上腺素能介导的心血管高反应性影响。在本研究中，我们比较了20名白人及17名黑人年轻血压正常男性对心算的心血管反应。与预期相反，黑人受试者的心率、收缩压和舒张压变化明显较小。这些发现表明，与白人相比，一些血压正常的黑人对已知会产生β-肾上腺素能介导反应的精神应激源的心血管反应性可能较低。
