MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, P. R. China.
Dalton Trans. 2021 Jun 8;50(22):7554-7562. doi: 10.1039/d1dt00889g.
A special functional group mediated functionalization platform is introduced as a new and versatile platform tool to improve the fluorescence detection performance of metal-organic frameworks (MOF). The creation of a mixed-functionalization strategy on a MOF realizes the high sensitivity detection of heavy metal ions, anions and small molecules. In this work, we have first reported a novel amino functionalized 3D indium MOF [In(BDC-NH2)(OH)]n (In1-NH2) which not only has an excellent fluorescent characteristic but also shows highly sensitive identification of Fe3+, Cu2+, Pb2+ and ClO- in water with broad linear ranges and short response times. Subsequently, based on the remaining amino group site of In1-NH2, a post-synthetic modification strategy is utilized to introduce an active boronic acid group for hydrogen peroxide detection. The obtained PBA-In1 exhibits an efficient sensing performance for hydrogen peroxide with an LOD of 0.42 μM. Given this, PBA-In1 is expected to become an effective probe to monitor the formation of metabolites in humans. In1-NH2 successfully achieves multiple ion detection and the PBA-In1 sensing platform with boronic acid functionalization may have good application prospects in biochemical research in the future.
引入了一种特殊的功能基团介导的功能化平台，作为一种新的多功能平台工具，以提高金属有机骨架（MOF）的荧光检测性能。在 MOF 上实现混合功能化策略的创建，实现了对重金属离子、阴离子和小分子的高灵敏度检测。在这项工作中，我们首次报道了一种新型的氨基功能化 3D 铟 MOF [In(BDC-NH2)(OH)]n（In1-NH2），它不仅具有优异的荧光特性，而且还对水中的 Fe3+、Cu2+、Pb2+和 ClO-具有高度敏感的识别能力，具有较宽的线性范围和较短的响应时间。随后，基于 In1-NH2 中剩余的氨基位点，采用后合成修饰策略引入了活性硼酸基团，用于检测过氧化氢。所得的 PBA-In1 对过氧化氢表现出高效的传感性能，LOD 为 0.42 μM。鉴于此，PBA-In1 有望成为监测人体代谢物形成的有效探针。In1-NH2 成功实现了多种离子的检测，并且具有硼酸功能化的 PBA-In1 传感平台在未来的生化研究中可能具有良好的应用前景。
