Faculty of Medicine, Department of ENT, 209002İstanbul Yeni Yüzyıl University, İstanbul, Turkey.
Department of Internal Medicine, 209002Bahat Hosphital, Sultangazi, İstanbul, Turkey.
Ear Nose Throat J. 2022 Sep;101(8):501-505. doi: 10.1177/01455613211012114. Epub 2021 May 11.
As a result of the COVID-19 pandemic that occurred in the last year, it has been revealed that severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) does not only cause viral respiratory tract infection but can also affect many organs in the short or long term. In our study, we aimed to reveal that COVID-19 infection affects the endocrine system and triggers subacute thyroiditis (SAT) in the acute period.
In our retrospective study, the ear-nose-throat examination, internal diseases consultation (investigation of COVID-19 symptoms and polymerase chain reaction [PCR] test), routine blood tests, T3, T4, thyroid-stimulating hormone, antithyroglobulin (anti-TG), antithyroid peroxidase (anti-TPO), thyroid scintigraphy, and thyroid ultrasonography results of 5 patients who applied to the otorhinolaryngology clinic due to complaints of neck pain and odynophagia between April 2020 and February 2021 were examined.
All 5 patients were female patients (30.4 years) with odynophagia and pain in the front lower region of the neck. These patients had no previous history of thyroiditis. COVID-19 PCR tests of the patients diagnosed with SAT were positive, and there were no typical COVID-19 signs and symptoms except odynophagia and neck pain.
It comes in view that SARS-COV-2 affects thyroid functions and causes SAT and the main symptoms in patients are pain in the neck and odynophagia.
由于去年发生的 COVID-19 大流行,已经表明严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)不仅会引起病毒性呼吸道感染,而且还会在短期或长期内影响许多器官。在我们的研究中,我们旨在揭示 COVID-19 感染会影响内分泌系统并在急性期引发亚急性甲状腺炎(SAT)。
在我们的回顾性研究中,对因颈痛和咽痛而于 2020 年 4 月至 2021 年 2 月间就诊耳鼻喉科的 5 例患者进行了耳鼻喉检查、内科咨询(调查 COVID-19 症状和聚合酶链反应(PCR)检测)、常规血液检查、T3、T4、促甲状腺激素、抗甲状腺球蛋白(抗-TG)、抗甲状腺过氧化物酶(抗-TPO)、甲状腺闪烁显像和甲状腺超声检查。
所有 5 例患者均为女性(30.4 岁),有咽痛和颈前下部疼痛。这些患者均无甲状腺炎既往史。经 SAT 诊断的患者的 COVID-19 PCR 检测呈阳性,除咽痛和颈痛外,无典型 COVID-19 体征和症状。
SARS-COV-2 会影响甲状腺功能并导致 SAT,患者的主要症状为颈部疼痛和咽痛。