神经发育：比较连接组学与回路组装研究。

Neurodevelopment: Comparative connectomics and the study of circuit assembly.

机构信息

MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

出版信息

Curr Biol. 2021 May 10;31(9):R452-R454. doi: 10.1016/j.cub.2021.03.053.

DOI:10.1016/j.cub.2021.03.053

Abstract

A new study reveals the effects of specific single cell type perturbations on the assembly and function of a mechanosensory circuit in the Drosophila melanogaster larva with synaptic resolution. This work paves the way for the use of comparative connectomics to understand general principles governing the development of wiring specificity.

摘要

一项新的研究揭示了特定单细胞类型扰动对具有突触分辨率的果蝇幼虫机械感觉回路组装和功能的影响。这项工作为利用比较连接组学来理解支配布线特异性发育的一般原则铺平了道路。