Department of Zoology, University of Cambridge, United Kingdom.
Department of Zoology, University of Cambridge, United Kingdom; MRC Laboratory of Molecular Biology, United Kingdom.
Curr Opin Neurobiol. 2020 Dec;65:129-137. doi: 10.1016/j.conb.2020.09.008. Epub 2020 Nov 23.
The larva of Drosophila melanogaster is emerging as a powerful model system for comprehensive brain-wide understanding of the circuit implementation of neural computations. With an unprecedented amount of tools in hand, including synaptic-resolution connectomics, whole-brain imaging, and genetic tools for selective targeting of single neuron types, it is possible to dissect which circuits and computations are at work behind behaviors that have an interesting level of complexity. Here we present some of the recent advances regarding multisensory integration, learning, and action selection in Drosophila larva.
黑腹果蝇的幼虫正逐渐成为一个强大的模型系统,可用于全面了解神经计算的全脑范围的电路实现。凭借包括突触分辨率连接组学、全脑成像以及用于选择性靶向单一神经元类型的遗传工具等前所未有的大量工具,可以剖析在具有有趣复杂程度的行为背后起作用的是哪些电路和计算。在这里,我们介绍了黑腹果蝇幼虫在多感觉整合、学习和动作选择方面的一些最新进展。