Heyming Theodore W, Knudsen-Robbins Chloe, Feaster William, Ehwerhemuepha Louis
Children's Hospital of Orange County, Orange, CA, United States; Department of Emergency Medicine, University of California, Irvine, United States.
University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Am J Emerg Med. 2021 Oct;48:209-217. doi: 10.1016/j.ajem.2021.05.004. Epub 2021 May 6.
To develop and analyze the performance of a machine learning model capable of predicting the disposition of patients presenting to a pediatric emergency department (ED) based on triage assessment and historical information mined from electronic health records.
We retrospectively reviewed data from 585,142 ED visits at a pediatric quaternary care institution between 2013 and 2020. An extreme gradient boosting machine learning model was trained on a randomly selected training data set (50%) to stratify patients into 3 classes: (1) high criticality (patients requiring intensive care unit [ICU] care within 4 h of hospital admission, patients who died within 4 h of admission, and patients who died in the ED); (2) moderate criticality (patients requiring hospitalization without the need for ICU care); and (3) low criticality (patients discharged home). Variables considered during model development included triage vital signs, aspects of triage nursing assessment, demographics, and historical information (diagnoses, medication use, and healthcare utilization). Historical factors were limited to the 6 months preceding the index ED visit. The model was tested on a previously withheld test data set (40%), and its performance analyzed.
The distribution of criticality among high, moderate, and low was 1.5%, 7.1%, and 91.4%, respectively. The one-versus-all area under the receiver operating characteristic (AUROC) curve for high and moderate criticality was 0.982 (95% CI 0.980, 0.983) and 0.968 (0.967, 0.969). The multi-class macro average AUROC and area under the receiver operating characteristic curve were 0.976 and 0.754. The features most integral to model performance included history of intravenous medications, capillary refill, emergency severity index level, history of hospitalization, use of a supplemental oxygen device, age, and history of admission to the ICU.
Pediatric ED disposition can be accurately predicted using information available at triage, providing an opportunity to improve quality of care and patient outcomes.
开发并分析一种机器学习模型的性能,该模型能够根据分诊评估和从电子健康记录中挖掘的历史信息,预测儿科急诊科(ED)患者的处置情况。
我们回顾性分析了2013年至2020年期间一家儿科四级医疗机构585142次急诊就诊的数据。在随机选择的训练数据集(50%)上训练一个极端梯度提升机器学习模型,将患者分为3类:(1)高危急度(入院后4小时内需重症监护病房[ICU]护理的患者、入院后4小时内死亡的患者以及在急诊科死亡的患者);(2)中度危急度(需要住院但无需ICU护理的患者);(3)低危急度(出院回家的患者)。模型开发过程中考虑的变量包括分诊生命体征、分诊护理评估方面、人口统计学信息以及历史信息(诊断、用药情况和医疗保健利用情况)。历史因素仅限于本次急诊就诊前6个月。该模型在先前保留的测试数据集(40%)上进行测试,并分析其性能。
高、中、低危急度的分布分别为1.5%、7.1%和91.4%。高危急度和中度危急度的一对一受试者工作特征(AUROC)曲线下面积分别为0.982(95%CI 0.980, 0.983)和0.968(0.967, 0.969)。多类宏平均AUROC和受试者工作特征曲线下面积分别为0.976和0.754。对模型性能最为重要的特征包括静脉用药史、毛细血管再充盈情况、急诊严重程度指数水平、住院史、使用补充氧气设备情况、年龄以及入住ICU史。
利用分诊时可得的信息能够准确预测儿科急诊处置情况,为改善护理质量和患者结局提供了机会。