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The CYP2C19 genotypes and its effect on clopidogrel as an anti-platelet drug among the Arab population.

作者信息

Alkattan Abdullah, Almutairi Yousef, Alsalameen Eman, Alkhalifah Ahmed, Alghanim Fatimah

机构信息

Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Hofuf, Al-Ahsa; Department of Research and Development, Chronic Disease Prevention Center, Ministry of Health, Riyadh, Saudi Arabia.

Department of Research and Development, Chronic Disease Prevention Center, Ministry of Health, Riyadh, Saudi Arabia.

出版信息

Indian J Pharmacol. 2021 Jan-Feb;53(1):85-87. doi: 10.4103/ijp.IJP_690_20.

DOI:10.4103/ijp.IJP_690_20
PMID:33976007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8216117/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/8216117/e0b07c08be89/IJPharm-53-85-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/8216117/e0b07c08be89/IJPharm-53-85-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/8216117/e0b07c08be89/IJPharm-53-85-g001.jpg

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本文引用的文献

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Eur Cardiol. 2018 Dec;13(2):115-118. doi: 10.15420/ecr.2018.12.2.
2
Reduction of cardiovascular risk in subjects with high lipoprotein (a) levels.降低高脂蛋白（a）水平受试者的心血管风险。
J Thorac Dis. 2017 Aug;9(8):2332-2336. doi: 10.21037/jtd.2017.08.67.
3
Pharmacogenetics of CYP2C19 genetic polymorphism on clopidogrel response in patients with ischemic stroke from Saudi Arabia.
沙特阿拉伯缺血性中风患者中CYP2C19基因多态性对氯吡格雷反应的药物遗传学研究
Neurosciences (Riyadh). 2017 Jan;22(1):31-37. doi: 10.17712/nsj.2017.1.20160303.
4
Genetic and Nongenetic Factors Affecting Clopidogrel Response in the Egyptian Population.影响埃及人群氯吡格雷反应的遗传和非遗传因素
Clin Transl Sci. 2016 Feb;9(1):23-8. doi: 10.1111/cts.12383. Epub 2016 Jan 12.
5
Impact of Cytochrome P450 2C19*2 and *3 on Clopidogrel Loading Dose in Saudi Patients with Acute Coronary Syndrome.细胞色素P450 2C19*2和*3对沙特急性冠状动脉综合征患者氯吡格雷负荷剂量的影响
Drug Metab Lett. 2016;10(1):65-70. doi: 10.2174/1872312810666151117122841.
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