Cutts Julia C, Quinn Brendan, Seed Clive R, Kotsiou George, Pearson Ruth, Scott Nick, Wilson David P, Harrod Mary Ellen, Maher Lisa, Caris Sharon, Thompson Alex J, Farrell Michael, Pink Joanne, Hellard Margaret E
Burnet Institute, Melbourne, Victoria, Australia.
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Transfus Med Hemother. 2021 Mar;48(2):118-129. doi: 10.1159/000509027. Epub 2020 Jul 23.
Pre-donation screening of potential blood donors is critical for ensuring the safety of the donor blood supply, and donor deferral as a result of risk factors is practised worldwide. This systematic review was conducted in the context of an expert review convened by the Australian Red Cross Lifeblood in 2013 to consider Lifeblood's injecting drug use (IDU)-related policies and aimed to identify studies assessing interventions to improve compliance with deferral criteria in blood donation settings.
MEDLINE/PubMed, OVID Medline, OVID Embase, LILACS, and the Cochrane Library (CENTRAL and DARE) databases were searched for studies conducted within blood donation settings that examined interventions to increase blood donor compliance with deferral criteria. Observational and experimental studies from all geographical areas were considered.
Ten studies were identified that tested at least one intervention to improve blood donor compliance with deferral criteria, including computerized interviews or questionnaires, direct and indirect oral questioning, educational materials, and a combination of a tickbox questionnaire and a personal donor interview. High-quality evidence from a single study was provided for the effectiveness of a computerized interview in improving detection of HIV risk behaviour. Low-quality evidence for the effectiveness of computerized interviews was provided by 3 additional studies. Two studies reported a moderate effect of direct questioning in increasing donor deferral, but the quality of the evidence was low.
This review identified several interventions to improve donor compliance that have been tested in blood donation settings and provided evidence for the effectiveness of computerized interviews in improving detection of risk factors.
对潜在献血者进行献血前筛查对于确保供血安全至关重要，因风险因素导致的献血者延期在全球范围内都有实施。本系统评价是在澳大利亚红十字会生命血液组织于2013年召集的一次专家评审背景下进行的，旨在审议生命血液组织与注射吸毒（IDU）相关的政策，其目的是确定评估在献血环境中提高对延期标准依从性的干预措施的研究。
检索MEDLINE/PubMed、OVID Medline、OVID Embase、LILACS以及Cochrane图书馆（CENTRAL和DARE）数据库，查找在献血环境中进行的、检验提高献血者对延期标准依从性干预措施的研究。考虑所有地理区域的观察性和实验性研究。
共识别出10项研究，这些研究测试了至少一种提高献血者对延期标准依从性的干预措施，包括计算机化访谈或问卷调查、直接和间接口头询问、教育材料，以及勾选框问卷和个人献血者访谈相结合的方式。一项单一研究提供了关于计算机化访谈在改善HIV风险行为检测方面有效性的高质量证据。另外3项研究提供了关于计算机化访谈有效性的低质量证据。两项研究报告了直接询问在增加献血者延期方面有中等效果，但证据质量较低。
本评价确定了几种在献血环境中已测试过的提高献血者依从性的干预措施，并提供了计算机化访谈在改善风险因素检测方面有效性的证据。
