短暂性视力丧失——一种罕见的奥沙利铂所致眼科副作用：两例报告
Transient Vision Loss - A Rare Oxaliplatin-Induced Ophthalmologic Side Effect: A Report of Two Cases.
作者信息
Ah-Thiane Loic, Raoul Jean-Luc, Hiret Sandrine, Senellart Hélène, Dumont Frédéric, Raimbourg Judith
机构信息
Department of Medical Oncology, Institut de Cancérologie de l'Ouest, Saint-Herblain, France.
Department of Surgical Oncology, Institut de Cancérologie de l'Ouest, Saint-Herblain, France.
出版信息
Case Rep Oncol. 2021 Mar 18;14(1):483-486. doi: 10.1159/000514656. eCollection 2021 Jan-Apr.
Abstract
Oxaliplatin, a platinum-based chemotherapeutic agent, is responsible for induced peripheral sensory neuropathy. Only a few cases of ophthalmologic toxicity have been reported. We report here two cases of sudden transient vision loss after oxaliplatin administration, in one case intraperitoneally. These symptoms likely reflect optic neuritis that could be included in the spectrum of oxaliplatin-induced neuropathy.
摘要
奥沙利铂是一种铂类化疗药物，可导致外周感觉神经病变。仅报告过少数几例眼科毒性病例。我们在此报告两例奥沙利铂给药后突然出现短暂视力丧失的病例，其中一例为腹腔内给药。这些症状可能反映了视神经炎，它可能属于奥沙利铂诱导的神经病变范畴。
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