Department of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Department of Radiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Pediatr Radiol. 2021 Nov;51(12):2214-2228. doi: 10.1007/s00247-020-04868-x. Epub 2021 May 12.
Contrast-enhanced ultrasound (CEUS) has emerged as a valuable modality for bowel imaging in adults and children. CEUS enables visualization of the perfusion of the bowel wall and of the associated mesentery in healthy and disease states. In addition, CEUS images can be used to make quantitative measurements of contrast kinetics, allowing for objective assessment of bowel wall enhancement. Bowel CEUS is commonly applied to evaluate inflammatory bowel disease and to monitor treatment response. It has also been applied to evaluate necrotizing enterocolitis, intussusception, appendicitis and epiploic appendagitis, although experience with these applications is more limited. In this review article, we present the current experience using CEUS to evaluate the pediatric bowel with emphasis on inflammatory bowel disease, extrapolating the established experience from adult studies. We also discuss emerging applications of CEUS as an adjunct or problem-solving tool for evaluating bowel perfusion.
对比增强超声（CEUS）已成为成人和儿童肠道成像的一种有价值的方式。CEUS 能够可视化健康和疾病状态下肠壁和相关肠系膜的灌注。此外，CEUS 图像可用于对对比剂动力学进行定量测量，从而客观评估肠壁增强。肠道 CEUS 通常用于评估炎症性肠病和监测治疗反应。它也已应用于评估坏死性小肠结肠炎、肠套叠、阑尾炎和阑尾炎，尽管在这些应用方面的经验更为有限。在这篇综述文章中，我们介绍了使用 CEUS 评估儿科肠道的当前经验，重点是炎症性肠病，并从成人研究中推断出既定的经验。我们还讨论了 CEUS 作为评估肠道灌注的辅助或解决问题工具的新应用。
