乳寡糖，N-岩藻糖基乳糖，可抑制小鼠囊胚附着于子宫内膜单层细胞。
The milk oligosaccharide, lacto-N-fucopentaose I, inhibits attachment of mouse blastocysts on endometrial monolayers.
作者信息
Lindenberg S, Sundberg K, Kimber S J, Lundblad A
机构信息
Department of Obstetrics and Gynaecology, Rigshospitalet, University of Copenhagen, Denmark.
出版信息
J Reprod Fertil. 1988 May;83(1):149-58. doi: 10.1530/jrf.0.0830149.
Seven oligosaccharides isolated from human milk were tested for their effect in an in-vitro model of mouse blastocyst adhesion and trophoblast outgrowth on endometrial epithelial monolayers. One compound, lacto-N-fucopentaose I (LNF I), produced a significant reduction in the percentage of attached and outgrown blastocysts after co-culture for 72 h (P less than 0.001). No significant effect of any other tested oligosaccharide was obtained.
从人乳中分离出的七种低聚糖在小鼠囊胚黏附及滋养层细胞在子宫内膜上皮单层上生长的体外模型中进行了效果测试。其中一种化合物，乳糖-N-岩藻五糖I（LNF I），在共培养72小时后，使黏附及生长的囊胚百分比显著降低（P小于0.001）。其他测试的低聚糖均未产生显著效果。
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