Cattafi Antonino, Galeano Mariarosaria, Pitrone Pietro, Sofia Carmelo, Marino Maria Adele, Ascenti Giorgio, Lentini Maria, Ieni Antonio, Cardia Roberta, Costa Alfio Luca, Familiari Dario, Barone Mario, Monaco Francesco, Colonna Michele Rosario
Department of Biomedical Sciences and Morphologic and Functional Imaging, Policlinico Universitario "G.Martino", University of Messina, Messina, Italy.
Department of Human Pathology of the Adult, the Child and the Adolescent, Policlinico Universitario "G. Martino", University of Messina, Messina, Italy.
Radiol Case Rep. 2021 Apr 19;16(6):1557-1563. doi: 10.1016/j.radcr.2021.03.039. eCollection 2021 Jun.
Nodular fasciitis is a benign tumor of soft tissues originating from the proliferation of fibroblasts and myofibroblasts, generally developing between the subcutaneous tissue and the underlying muscular layer. Nodular fasciitis predominantly localizes in the upper extremities, trunk, head and neck. Biomolecular and immunohistochemical analyses result essential to demonstrate the benign origin of the process, also confirmed by very low recurrence rate after complete excision, which represents the gold standard for treatment. We report the case of a 36 years-old man who developed a nodular protuberance clinically evident in the upper-left side of the thorax. We further, highlight the main characteristics of this rare neoplasm trough a thorough review of the literature.
结节性筋膜炎是一种软组织良性肿瘤,起源于成纤维细胞和平滑肌肌成纤维细胞的增殖,通常发生于皮下组织和其下方的肌肉层之间。结节性筋膜炎主要位于上肢、躯干、头颈部。生物分子和免疫组织化学分析对于证明该病变的良性起源至关重要,完全切除后极低的复发率也证实了这一点,完全切除是治疗的金标准。我们报告了一例36岁男性患者,其在左胸上部出现临床上明显的结节状隆起。我们还通过对文献的全面回顾,突出了这种罕见肿瘤的主要特征。