Psychiatric Liaison Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Department of General Internal Medicine and Psychosomatics, Medical University Hospital, Heidelberg, Germany.
Obes Surg. 2021 Sep;31(9):3996-4004. doi: 10.1007/s11695-021-05440-8. Epub 2021 May 12.
While bariatric surgery is an effective therapy for patients with severe obesity, not all patients benefit equally. An explanation might be that psychosocial risk factors hamper outcome. The study aimed to evaluate if biopsychosocial case complexity predicts evolution of BMI over 10 years after bariatric surgery.
Charts of patients (N = 236) of the Cohort of Obesity Lausanne (COOL) were retrospectively reviewed and rated with the INTERMED, a reliable and validated instrument, which assesses biopsychosocial case complexity and has been proven to predict outcome of medical treatments in different patient populations. The sample was stratified into BMI quartiles, computed from the patients' baseline BMI. For each quartile, BMI evolution was analyzed using individual growth curve analysis.
Growth curve analyses showed that in quartiles 1, 2, and 3, none of the INTERMED domain scores significantly predicted the BMI evolution after surgery. However, in the fourth quartile-including patients with the highest pre-surgical BMI-the social domain score of the INTERMED significantly predicted BMI evolution: patients with more social complexity showed higher increase in BMI.
Effectiveness of interventions targeted at social complexity, especially when patients suffer from severe obesity, may therefore be evaluated in future studies.
虽然减重手术是治疗重度肥胖患者的有效方法,但并非所有患者都能从中受益。一种解释可能是心理社会风险因素阻碍了治疗效果。本研究旨在评估生物心理社会病例复杂性是否可以预测减重手术后 10 年内 BMI 的变化。
回顾性分析了洛桑肥胖队列(COOL)患者的病历(N=236),并使用 INTERMED 进行评分。INTERMED 是一种可靠且经过验证的工具,可评估生物心理社会病例复杂性,并已证明可预测不同患者群体的医疗治疗结果。该样本按患者基线 BMI 的四分位数分层。对于每个四分位数,使用个体生长曲线分析来分析 BMI 的演变。
生长曲线分析表明,在四分位数 1、2 和 3 中,INTERMED 的任何一个领域评分都不能显著预测手术后 BMI 的变化。然而,在包括术前 BMI 最高的患者的第四四分位数中,INTERMED 的社会领域评分显著预测了 BMI 的演变:社会复杂性较高的患者 BMI 增加更高。
因此,未来的研究可能需要评估针对社会复杂性的干预措施的有效性,尤其是针对患有严重肥胖症的患者。