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将静脉阻力纳入户川用于盖顿循环平衡的四象限图中。

Incorporation of venous resistance in Togawa's four quadrant diagram for Guyton's circulatory equilibrium.

作者信息

Suga H

机构信息

Department of Cardiovascular Dynamics, National Cardiovascular Center, Osaka, Japan.

出版信息

Jpn Heart J. 1988 Jan;29(1):89-98. doi: 10.1536/ihj.29.89.

DOI:10.1536/ihj.29.89
PMID:3398246
Abstract

Guyton indicates that the contribution of venous resistance to venous return resistance is magnified by the compliance ratio (30) of the venous compartment to the arterial compartment. Therefore, even a slightly increased venous resistance sensitively decreases venous return and hence cardiac output in the circulatory equilibrium. However, Guyton's diagram does not allow an easy and explicit evaluation of the effect of venous resistance on cardiac output. The circulatory equilibrium can be visualized graphically by Togawa's four quadrant diagram. However, Togawa's diagram does not include venous resistance. Therefore, I modified Togawa's diagram to incorporate venous resistance in the first quadrant for the cardiac output curve. The new diagram shows easily and explicitly that venous resistance sensitively tilts down either the venous return curve or the cardiac output curve and markedly decreases venous return and cardiac output.

摘要

盖顿指出,静脉阻力对静脉回心血量阻力的贡献会因静脉腔与动脉腔的顺应性比值(30)而放大。因此,即使静脉阻力稍有增加,也会在循环平衡状态下敏感地降低静脉回心血量,进而降低心输出量。然而,盖顿的图表并不便于对静脉阻力对心输出量的影响进行简单而明确的评估。循环平衡可以通过户川的四象限图以图形方式直观呈现。然而,户川的图表并未包含静脉阻力。因此,我对户川的图表进行了修改,在第一象限的心输出量曲线中纳入了静脉阻力。新图表清晰明了地显示,静脉阻力会使静脉回心血量曲线或心输出量曲线敏感地下倾,并显著降低静脉回心血量和心输出量。

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引用本文的文献

1
An interactive simulator to deepen the understanding of Guyton's venous return curve.一个交互式模拟器,用于加深对盖顿静脉回流曲线的理解。
J Physiol Sci. 2024 Mar 30;74(1):21. doi: 10.1186/s12576-024-00912-9.