Kim Mi Young
Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea.
Adv Exp Med Biol. 2021;1187:183-204. doi: 10.1007/978-981-32-9620-6_9.
Owing to increased awareness of the importance of mammogram and advances in surgical technology, survival rate of patients with primary breast cancer has dramatically increased. Despite all these advances in breast cancer treatment, there are no currently available treatments for this disease once it metastasizes to distant organs including bones, lungs, brain, and liver. This is mainly attributed to the complexity of metastatic process. Recent advances in technology enabled cancer biologists to dissect each step of the metastatic process, and this led to discovery of major players and molecules in this process. In this section, we will discuss recent discovery and advances in the field of breast cancer metastasis research.
由于对乳房X光检查重要性的认识提高以及外科技术的进步,原发性乳腺癌患者的生存率显著提高。尽管乳腺癌治疗取得了所有这些进展,但一旦这种疾病转移到包括骨骼、肺部、大脑和肝脏在内的远处器官,目前尚无针对该疾病的有效治疗方法。这主要归因于转移过程的复杂性。技术上的最新进展使癌症生物学家能够剖析转移过程的每一步,这导致了该过程中主要参与者和分子的发现。在本节中,我们将讨论乳腺癌转移研究领域的最新发现和进展。