Current Address: Department of Biology, University of Maryland, College Park, Maryland, 20742.
Department of Biology, University of Virginia, Charlottesville, Virginia, 22904.
Evolution. 2021 Oct;75(10):2494-2508. doi: 10.1111/evo.14264. Epub 2021 Jun 9.
Determining the processes that drive the evolution of pathogen host range can inform our understanding of disease dynamics and the potential for host shifts. In natural populations, patterns of host range could be driven by genetically based differences in pathogen infectivity or ecological differences in host availability. In northwestern Italy, four reproductively isolated lineages of the fungal plant-pathogen Microbotryum have been shown to co-occur on several species in the genus Dianthus. We carried out cross-inoculation experiments to determine whether patterns of realized host range in these four lineages were driven by differences in infectivity and to test whether there was evidence of a trade-off between host range and within-host reproduction. We found strong concordance between field patterns of host range and pathogen infectivity on different Dianthus species using experimental inoculation, indicating that infection ability is a major driving force of host range. However, we found no evidence of a trade-off between the ability to infect a wider range of host species and spore production on a shared host.
确定驱动病原体宿主范围进化的过程可以帮助我们理解疾病动态和宿主转移的潜力。在自然种群中，宿主范围的模式可能是由病原体感染力的遗传基础差异或宿主可利用性的生态差异驱动的。在意大利西北部，已经表明真菌植物病原体 Microbotryum 的四个生殖隔离谱系共同存在于石竹属的几个物种中。我们进行了交叉接种实验，以确定这四个谱系中实际宿主范围的模式是否由感染力的差异驱动，并检验在宿主范围和体内繁殖之间是否存在权衡。我们发现，使用实验接种，宿主范围的野外模式与不同石竹属物种上的病原体感染力之间存在很强的一致性，表明感染能力是宿主范围的主要驱动力。然而，我们没有发现感染更广泛宿主物种的能力与在共享宿主上产生孢子的能力之间存在权衡的证据。
