Elmashala Amjad, Chopra Saurav, Garg Aayushi
Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
J Neurol Res. 2020 Aug;10(4):107-112. doi: 10.14740/jnr603. Epub 2020 Jun 23.
The coronavirus disease 2019 (COVID-19) is an ongoing global pandemic that has so far affected 216 countries and more than 5 million individuals worldwide. The infection is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While pulmonary manifestations are the most common, neurological features are increasingly being recognized as common manifestations of the COVID-19, especially in the cases of severe infection. These include acute cerebrovascular disease, encephalitis, and Guillain-Barre syndrome (GBS). Here, we review the neuropathogenesis of SARS-CoV-2 and the central and peripheral nervous system manifestations of COVID-19.
2019冠状病毒病（COVID-19）是一场仍在持续的全球大流行疾病，迄今为止已影响到全球216个国家和500多万人。该感染由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起。虽然肺部表现最为常见，但神经学特征越来越被认为是COVID-19的常见表现，尤其是在重症感染病例中。这些表现包括急性脑血管疾病、脑炎和吉兰-巴雷综合征（GBS）。在此，我们综述SARS-CoV-2的神经发病机制以及COVID-19的中枢和外周神经系统表现。
