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孕妇报告称被拒绝使用药物来治疗严重的妊娠恶心和呕吐或妊娠剧吐——来自澳大利亚在线调查的结果。

Pregnant women report being denied medications to treat severe nausea and vomiting of pregnancy or hyperemesis gravidarum - findings from an Australian online survey.

机构信息

SA Pharmacy, Flinders Medical Centre, SA Health, Adelaide, South Australia, Australia.

Hyperemesis Australia, Sydney, New South Wales, Australia.

出版信息

Aust N Z J Obstet Gynaecol. 2021 Aug;61(4):616-620. doi: 10.1111/ajo.13359. Epub 2021 May 13.

DOI:10.1111/ajo.13359
PMID:33984156
Abstract

We conducted an online survey of 249 Australian women who currently or previously experienced severe nausea and vomiting of pregnancy (NVP) or hyperemesis gravidarum (HG) and examined their experiences in being denied medications during pregnancy. One in four women reported being denied medications for NVP/HG, which most commonly involved doxylamine and encounters with community pharmacists. Women's experiences reflected that lack of awareness of guidelines and unfavourable risk-benefit assessments appeared to be key barriers to facilitating medication access. Approaches towards identifying and effectively addressing barriers to the provision of effective treatments for severe NVP and HG are urgently needed.

摘要

我们对 249 名目前或曾经经历过严重妊娠恶心和呕吐(NVP)或妊娠剧吐(HG)的澳大利亚女性进行了在线调查,并研究了她们在怀孕期间被拒绝用药的经历。四分之一的女性报告说被拒绝使用 NVP/HG 的药物,其中最常见的是羟嗪和与社区药剂师的接触。女性的经历反映出缺乏对指南的认识和对风险效益评估的不利,这似乎是阻碍药物获得的关键因素。迫切需要寻找并有效解决为严重 NVP 和 HG 提供有效治疗的障碍。

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1
Pregnant women report being denied medications to treat severe nausea and vomiting of pregnancy or hyperemesis gravidarum - findings from an Australian online survey.孕妇报告称被拒绝使用药物来治疗严重的妊娠恶心和呕吐或妊娠剧吐——来自澳大利亚在线调查的结果。
Aust N Z J Obstet Gynaecol. 2021 Aug;61(4):616-620. doi: 10.1111/ajo.13359. Epub 2021 May 13.
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引用本文的文献

1
Assessing the burden of severe nausea and vomiting of pregnancy or hyperemesis gravidarum and the associated use and experiences of medication treatments: An Australian consumer survey.评估妊娠剧吐或妊娠剧吐的严重恶心和呕吐负担以及药物治疗的相关使用情况和体验:一项澳大利亚消费者调查。
PLoS One. 2025 Sep 3;20(9):e0329687. doi: 10.1371/journal.pone.0329687. eCollection 2025.
2
How the structural determinants of health inequities impact access to prescription medication for pregnant women in Australia: a narrative review.澳大利亚健康不平等的结构决定因素如何影响孕妇获得处方药的机会:一项叙述性综述。
Lancet Reg Health West Pac. 2023 Oct 10;42:100934. doi: 10.1016/j.lanwpc.2023.100934. eCollection 2024 Jan.
3
Assessment of management approaches for hyperemesis gravidarum and nausea and vomiting of pregnancy: a retrospective questionnaire analysis.
妊娠剧吐和妊娠恶心呕吐管理方法评估:回顾性问卷调查分析。
BMC Pregnancy Childbirth. 2022 Aug 1;22(1):609. doi: 10.1186/s12884-022-04922-6.