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手术和腹腔内热化疗在卵巢癌中的作用。

Role of surgery and hyperthermic intraperitoneal chemotherapy in ovarian cancer.

机构信息

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.

出版信息

ESMO Open. 2021 Jun;6(3):100149. doi: 10.1016/j.esmoop.2021.100149. Epub 2021 May 10.

Abstract

Ovarian cancer is one of the deadliest gynaecological malignancies and tends to be diagnosed at an advanced stage. Similar to many malignancies, surgery plays a critical role in many aspects of ovarian cancer management. Hyperthermic intraperitoneal chemotherapy (HIPEC) involves the induction of hyperthermia and delivery of intraperitoneal chemotherapy directly into the peritoneal cavity. Combined with cytoreductive surgery, HIPEC is an emerging treatment modality for ovarian cancer. Ovarian cancer survival outcomes can be improved by treatment with surgery and HIPEC in selected patients. Thus, this study aimed to review the current role of surgery and HIPEC in epithelial ovarian cancer. Evidence from the monumental and recent literature will be introduced.

摘要

卵巢癌是一种致命的妇科恶性肿瘤,往往在晚期才被诊断出来。与许多恶性肿瘤一样,手术在卵巢癌的许多管理方面起着关键作用。腹腔内热灌注化疗(HIPEC)涉及诱导高热并将腹腔内化疗药物直接输送到腹腔内。HIPEC 联合细胞减灭术是治疗卵巢癌的一种新兴治疗方法。在选定的患者中,手术和 HIPEC 的联合治疗可以改善卵巢癌的生存结局。因此,本研究旨在回顾手术和 HIPEC 在卵巢上皮性癌中的作用。将介绍来自重要和最近文献的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8657/8314869/ff626c387854/gr1.jpg

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