Porche Ken, Lockney Dennis T, Gooldy Timothy, Kubilis Paul, Murad Gregory
College of Medicine, University of Florida, Gainesville, FL, USA; Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville, FL, USA.
College of Medicine, University of Florida, Gainesville, FL, USA; Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville, FL, USA.
Clin Neurol Neurosurg. 2021 Jun;205:106653. doi: 10.1016/j.clineuro.2021.106653. Epub 2021 Apr 25.
Surgical site infections (SSI) are a common post-operative complication, which increase cost, length of stay, and morbidity. Many risk factors have been, identified including body mass index (BMI). The purpose of this study was to evaluate, whether nuchal thickness rather than BMI increases risk for post-operative SSI in, posterior approach cervical spine operations.
A retrospective review of 180 patients who underwent posterior cervical spine, surgery at the University of Florida was performed. Nuchal thickness was measured, from the ventral most point of the spinous process of C5 to the skin on mid-sagittal preoperative, imaging. Diabetes status, BMI, smoking status, duration of anesthesia, prior, operations, and subcutaneous layer thickness was also collected. Infections were, identified according to the Centers for Disease Control (CDC) definitions for SSI. Univariate and multivariate analyses were performed by a biostatistician.
Twenty patients (11%) had SSI. Smoking status, nuchal thickness of greater, than 55 mm or less than 29.8 mm, and subcutaneous fat thickness were all associated, with SSI. Age (OR 0.99, p = 0.45), diabetes (OR 0.50, p = 0.37), BMI (OR 1.03, p = 0.35), and use of intraoperative antibiotic powder (OR 0.62, p = 0.35) were not associated with, infection. On multivariate analysis (adjusted for smoking status), nuchal thickness, (p < 0.0001), subcutaneous fat thickness (p < 0.0001), and the ratio of subcutaneous fat to, nuchal thickness (p < 0.0001) all remained associated with SSI.
Nuchal thickness and subcutaneous fat thickness are associated with SSI, in patients undergoing posterior cervical spine surgery. Risk of infection increases with very thin and very thick nuchal measurements.
手术部位感染(SSI)是一种常见的术后并发症,会增加费用、住院时间和发病率。已确定许多风险因素,包括体重指数(BMI)。本研究的目的是评估在颈椎后路手术中,颈部厚度而非BMI是否会增加术后SSI的风险。
对在佛罗里达大学接受颈椎后路手术的180例患者进行回顾性研究。在术前矢状面成像上,从C5棘突最腹侧点至皮肤测量颈部厚度。还收集了糖尿病状况、BMI、吸烟状况、麻醉持续时间、既往手术以及皮下层厚度。根据疾病控制中心(CDC)的SSI定义确定感染情况。由生物统计学家进行单因素和多因素分析。
20例患者(11%)发生SSI。吸烟状况、颈部厚度大于55mm或小于29.8mm以及皮下脂肪厚度均与SSI相关。年龄(OR 0.99,p = 0.45)、糖尿病(OR 0.50,p = 0.37)、BMI(OR 1.03,p = 0.35)以及术中使用抗生素粉剂(OR 0.62,p = 0.35)与感染无关。在多因素分析中(校正吸烟状况后),颈部厚度(p < 0.0001)、皮下脂肪厚度(p < 0.0001)以及皮下脂肪与颈部厚度之比(p < 0.0001)均仍与SSI相关。
在接受颈椎后路手术的患者中,颈部厚度和皮下脂肪厚度与SSI相关。颈部测量过薄和过厚时感染风险增加。