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非 Boerhaave 综合征患者食管破裂的适宜诊断与治疗:与 Boerhaave 综合征的比较

Suitable Diagnosis and Treatment of Esophageal Ruptures in Cases of Non-Boerhaave Syndrome: A Comparison With Boerhaave Syndrome.

机构信息

Nagoya City University, Nagoya City, Japan.

出版信息

J Investig Med High Impact Case Rep. 2021 Jan-Dec;9:23247096211014683. doi: 10.1177/23247096211014683.

Abstract

Boerhaave syndrome (BS) is frequently reported in cases of esophageal perforation; however, there are relatively few studies on non-Boerhaave syndrome (nBS). This study clarifies the appropriate diagnosis and treatment for patients with nBS among those with esophageal ruptures. Twelve patients with esophageal ruptures who underwent surgery at our department over 14 years were classified into 2 groups: 4 in the nBS group and 8 in the BS group. Patient characteristics, surgical methods, surgical outcomes, and complications were compared between the groups. The chief complaints varied between the groups. The nBS group had significantly higher preoperative C-reactive protein ( = .007) and required 5 days (median) from onset to surgery. Moreover, the perforation diameter was significantly smaller in the nBS group than in the BS group ( = .013). Suturing of the perforation site was performed during the initial surgery in 8 BS group patients (100%) and 1 nBS group patient (25%; = .018). Only drainage was performed during the initial surgery for 3 nBS group patients (75%). The complications did not significantly differ between the groups ( = 1.000), and no deaths were reported. The chief complaints of patients with nBS are diverse, and esophageal perforation should be cited as a differential diagnosis even in the absence of vomiting or chest pain symptoms. In the initial surgery for patients with nBS, the perforation site does not necessarily need to be closed. It is treatable by second-stage surgery or by natural closing.

摘要

布氏综合征(BS)常发生于食管穿孔病例中;然而,关于非布氏综合征(nBS)的研究相对较少。本研究旨在明确食管破裂患者中非布氏综合征的适当诊断和治疗方法。在过去 14 年中,我院对 12 例食管破裂患者进行了手术,将其分为 2 组:nBS 组 4 例,BS 组 8 例。比较了两组患者的一般情况、手术方法、手术结果和并发症。两组患者的主要症状不同。nBS 组患者术前 C 反应蛋白明显升高( =.007),发病至手术时间中位数为 5 天。此外,nBS 组穿孔直径明显小于 BS 组( =.013)。BS 组 8 例(100%)患者和 nBS 组 1 例(25%)患者( =.018)在初次手术中对穿孔部位进行缝合。nBS 组 3 例(75%)患者仅在初次手术中进行引流。两组患者的并发症无显著差异( = 1.000),且均无死亡病例。nBS 患者的主要症状多样,即使无呕吐或胸痛症状,也应将食管穿孔作为鉴别诊断。nBS 患者初次手术时,穿孔部位不一定需要缝合。二期手术或自然愈合即可治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ecb/8127747/b4483da5f7a5/10.1177_23247096211014683-fig1.jpg

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