Naitoh Hiroshi, Fukuchi Minoru, Kiriyama Shinsuke, Fukasawa Takaharu, Tabe Yuichi, Yamauchi Hayato, Yoshida Tomonori, Saito Kana, Hagiwara Kei, Kuwano Hiroyuki
1 Department of Surgery, Social Insurance Gunma Chuo General Hospital, Maebashi, Japan.
Int Surg. 2014 Nov-Dec;99(6):842-5. doi: 10.9738/INTSURG-D-13-00204.1.
A 52-year-old man was admitted to our hospital with a spontaneous esophageal rupture (Boerhaave syndrome) and was successfully treated. Eight years after the first incident, he was readmitted with a recurrent rupture. Recurrence of Boerhaave syndrome is extremely rare, with only 7 cases reported in the English literature. During treatment, the patient was also diagnosed with antiphospholipid syndrome (APS). Although APS is known to cause a variety of symptoms due to vascular thrombosis, recurrence of Boerhaave syndrome, coincident with APS, has never been reported. The pathogenesis of Boerhaave syndrome has not been clearly determined. This report serves to increase awareness of the risk of APS, which results in an increased risk of spontaneous rupture of the esophagus.
一名52岁男性因自发性食管破裂（Boerhaave综合征）入院并成功接受治疗。首次发病8年后，他因复发性破裂再次入院。Boerhaave综合征复发极为罕见，英文文献中仅报道过7例。治疗期间，该患者还被诊断出患有抗磷脂综合征（APS）。尽管已知APS会因血管血栓形成导致多种症状，但Boerhaave综合征与APS同时复发的情况此前从未有过报道。Boerhaave综合征的发病机制尚未明确确定。本报告旨在提高对APS风险的认识，APS会导致食管自发性破裂风险增加。
