Fantidis P, Gamalla Amat C, Fernández Ruiz M A, Madero Jarabo R, Moreno Granados F, Rubio D, Sanz Galeote E, De Miguel E
Department of Pathology, Hospital La Paz, Universidad Autónoma, Madrid, Spain.
J Thorac Cardiovasc Surg. 1988 Aug;96(2):299-303.
We studied pulmonary resistance as a surgical criterion for atriopulmonary shunt. We created a model of experimental pulmonary hypertension by establishing a systemic-pulmonary shunt in 11 dogs. Two to 3 months after the shunt operation, total pulmonary resistance was calculated before (7.24 +/- 1.54 U . m2) and after (3.50 +/- 1.54 U . m2) ligation of the shunt. An atriopulmonary anastomosis technique was then performed and the hemodynamic status of the dogs during the first 2 postoperative hours was evaluated. Pathologic study of the lungs disclosed no arterial lesions. From our experimental work, we conclude that the surgical criterion for establishing the indication for this operation should be pulmonary resistance, which is conditioned by the state of the intrapulmonary vessels. We propose a procedure for determining real pulmonary resistance in the course of preoperative catheterization.
我们研究了肺阻力作为心房肺分流术的手术标准。我们通过在11只狗身上建立体肺分流来创建实验性肺动脉高压模型。分流手术后2至3个月，在分流结扎前（7.24±1.54 U·m²）和结扎后（3.50±1.54 U·m²）计算总肺阻力。然后进行心房肺吻合技术，并评估狗术后前2小时的血流动力学状态。肺部的病理研究未发现动脉病变。从我们的实验工作中，我们得出结论，确定该手术适应症的手术标准应为肺阻力，其受肺内血管状态的制约。我们提出了一种在术前导管插入过程中确定实际肺阻力的方法。
