Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
Department of Health Security, Finnish Institute for Health and Welfare, Kuopio, Finland.
J Epidemiol Community Health. 2021 Nov;75(11):1111-1116. doi: 10.1136/jech-2021-216772. Epub 2021 May 13.
Air pollution has been suggested to be associated with depression. However, current evidence is conflicting, and no study has considered different sources of ambient particulate matter with an aerodynamic diameter below 2.5 µm (PM). We evaluated the associations of long-term exposure to PM from road traffic and residential wood combustion with the prevalence of depression in the Helsinki region, Finland.
We conducted a cross-sectional analysis based on the Helsinki Capital Region Environmental Health Survey 2015-2016 (N=5895). Modelled long-term outdoor concentrations of PM were evaluated using high-resolution emission and dispersion modelling on an urban scale and linked to the home addresses of study participants. The outcome was self-reported doctor-diagnosed or treated depression. We applied logistic regression and calculated the OR for 1 μg/m increase in PM, with 95% CI. Models were adjusted for potential confounders, including traffic noise and urban green space.
Of the participants, 377 reported to have been diagnosed or treated for depression by a doctor. Long-term exposure to PM from road traffic (OR=1.23, 95% CI 0.86 to 1.73; n=5895) or residential wood combustion (OR=0.78, 95% CI 0.43 to 1.41; n=5895) was not associated with the prevalence of depression. The estimates for PM from road traffic were elevated, but statistically non-significant, for non-smokers (OR=1.38, 95% CI 0.94 to 2.01; n=4716).
We found no convincing evidence of an effect of long-term exposure to PM from road traffic or residential wood combustion on depression.
空气污染与抑郁有关。然而，目前的证据存在矛盾，并且没有研究考虑到不同来源的环境细颗粒物（PM），其空气动力学直径小于 2.5μm。我们评估了来自道路交通和住宅木材燃烧的 PM 长期暴露与芬兰赫尔辛基地区抑郁患病率的关系。
我们基于 2015-2016 年赫尔辛基首都地区环境健康调查进行了一项横断面分析（N=5895）。使用城市尺度的高分辨率排放和扩散模型对 PM 的长期室外浓度进行建模，并将其与研究参与者的家庭住址相关联。结果是自我报告的经医生诊断或治疗的抑郁症。我们应用逻辑回归并计算了 PM 每增加 1μg/m 的比值比（OR），置信区间为 95%。模型调整了潜在的混杂因素，包括交通噪音和城市绿地。
在参与者中，有 377 人报告曾被医生诊断或治疗过抑郁症。长期暴露于道路交通产生的 PM（OR=1.23，95%CI 0.86 至 1.73；n=5895）或住宅木材燃烧产生的 PM（OR=0.78，95%CI 0.43 至 1.41；n=5895）与抑郁症的患病率无关。对于非吸烟者，道路交通产生的 PM 的估计值较高，但无统计学意义（OR=1.38，95%CI 0.94 至 2.01；n=4716）。
我们没有发现令人信服的证据表明长期暴露于道路交通或住宅木材燃烧产生的 PM 会对抑郁症产生影响。
