Remedios P A, Colletti P M, Raval J K, Benson R C, Chak L Y, Boswell W D, Halls J M
Department of Radiology, Los Angeles County-University of Southern California Medical Center 90033.
Magn Reson Imaging. 1988 May-Jun;6(3):301-4. doi: 10.1016/0730-725x(88)90406-7.
Magnetic resonance imaging (MRI) was performed in 22 patients at various times (0-3) years) following radiation therapy to the spine. T1 and T2 weighted images were obtained at 0.5 Tesla. Increased signal was seen after 800-6000 rads (8-60 Gy). Marrow effects corresponded to radiation ports. Recurrent tumor was clearly separated from fatty replacement. This was much better seen on T1 weighted images. Five patients that had MRI during their course of radiotherapy (XRT) did not have increased signal on T1 images of the bone marrow. The earliest fatty marrow change was seen nine days following completion of 3000 rads (30 Gy) XRT over one month's duration. One patient who received 800 rads (8 Gy) to the upper thoracic spine for eosinophilic granuloma had no radiation effects on MRI when imaged 16 days following completion of XRT given over five days. Fatty marrow change was seen in this patient on MRI six months later. MRI was particularly useful in defining the extent of prior radiation effects when repeat therapy was needed.
对22例接受脊柱放射治疗后的患者在不同时间（0至3年）进行了磁共振成像（MRI）检查。在0.5特斯拉磁场下获得了T1加权像和T2加权像。在接受800 - 6000拉德（8 - 60戈瑞）照射后可见信号增强。骨髓改变与放射野相对应。复发性肿瘤与脂肪替代可明显区分，在T1加权像上看得更清楚。5例在放射治疗（XRT）过程中进行MRI检查的患者，其骨髓T1像上未见信号增强。最早的脂肪骨髓改变见于为期1个月的3000拉德（30戈瑞）XRT结束后9天。1例因嗜酸性肉芽肿接受5天上胸部脊柱800拉德（8戈瑞）照射的患者，在5天的XRT结束后16天进行MRI检查时未发现放射效应。该患者6个月后的MRI显示有脂肪骨髓改变。当需要重复治疗时，MRI在确定既往放射效应的范围方面特别有用。
