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新冠疫情下法医病理学家的困境。

Forensic Pathologist's Dilemma in the wake of COVID-19 Pandemic.

机构信息

a:1:{s:5:"en_US";s:60:"Amity Institute of Forensic Sciences, Amity University, U.P.";}.

Amity Institute of Forensic Sciences, Amity University, U.P..

出版信息

Acta Biomed. 2021 May 12;92(2):e2021109. doi: 10.23750/abm.v92i2.11042.

DOI:10.23750/abm.v92i2.11042
PMID:33988149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8182614/
Abstract

The role of forensic pathologist is imperative for investigation of pathophysiological outcome of disease by conducting autopsy or post-mortem examination. Autopsy examination becomes highly significant when the cause of death is unknown or physicochemical parameters of death is of unknown nature due to novel emerging conditions as in case of novel coronavirus pandemic. In the wake of COVID-19 pandemic, there is undeniable amount of pressure on the forensic examiner fraternity due to the highly contagious nature of new coronavirus (SARS-CoV-2). Autopsy involves thorough external examination of the deceased body followed by gross internal, histopathological examination of organs and molecular analysis of body fluids for various tissue specific and blood biomarkers (enzymes, electrolytes, hormones) to ascertain disease progression and cause of death.

摘要

法医病理学家的角色对于通过进行尸检或死后检查来研究疾病的病理生理结果至关重要。当死因不明或由于新型新兴条件(如新型冠状病毒大流行)导致死亡的理化参数性质未知时,尸检检查变得非常重要。在 COVID-19 大流行之后,由于新型冠状病毒(SARS-CoV-2)具有高度传染性,法医检查人员面临着不可否认的巨大压力。尸检包括对死者尸体进行彻底的外部检查,然后对器官进行大体内部和组织病理学检查,并对体液进行分子分析,以确定各种组织特异性和血液生物标志物(酶、电解质、激素)的疾病进展和死因。

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本文引用的文献

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Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1.与严重急性呼吸综合征冠状病毒1(SARS-CoV-1)相比,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在气溶胶和表面的稳定性
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Supporting the Health Care Workforce During the COVID-19 Global Epidemic.在新冠疫情全球大流行期间为医护人员提供支持。
JAMA. 2020 Apr 21;323(15):1439-1440. doi: 10.1001/jama.2020.3972.
3
Reasons for healthcare workers becoming infected with novel coronavirus disease 2019 (COVID-19) in China.中国医护人员感染2019新型冠状病毒病(COVID-19)的原因。
J Hosp Infect. 2020 May;105(1):100-101. doi: 10.1016/j.jhin.2020.03.002. Epub 2020 Mar 6.
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Pathological findings of COVID-19 associated with acute respiratory distress syndrome.与急性呼吸窘迫综合征相关的新型冠状病毒肺炎的病理表现
Lancet Respir Med. 2020 Apr;8(4):420-422. doi: 10.1016/S2213-2600(20)30076-X. Epub 2020 Feb 18.
5
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.