Clinical Department of Internal Medicine and Specialistics, Department of Advanced Clinical and Surgical Sciences, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Pathol Res Pract. 2020 Nov;216(11):153195. doi: 10.1016/j.prp.2020.153195. Epub 2020 Aug 28.
During the COVID-19 pandemic, many deaths occurred especially among the old patients with cardiovascular comorbidities. Many questions have been asked and few simple answers have been given. The autopsy data are few and the aspects often observed are pulmonary diffuse alveolar damage (DAD), myocarditis, acute myocardial infarction (AMI), and disseminated intravascular coagulation (DIC); these aspects are not only in COVID-19 but also in other viral infections and in sepsis. It should be considered that coronavirus with its pathological organ changes have already been described in the years preceding the pandemic.
在 COVID-19 大流行期间,许多死亡病例发生在患有心血管合并症的老年患者中。人们提出了许多问题,但得到的简单答案却很少。尸检数据很少,而且通常观察到的方面是肺部弥漫性肺泡损伤 (DAD)、心肌炎、急性心肌梗死 (AMI) 和弥散性血管内凝血 (DIC);这些方面不仅存在于 COVID-19 中,也存在于其他病毒感染和脓毒症中。应当考虑到,在大流行之前的几年中,冠状病毒及其引起的病理器官变化已经被描述过。