Division of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla, California, USA.
Division of Biomedical Informatics, Department of Medicine, University of California San Diego, La Jolla, California, USA.
Inflamm Bowel Dis. 2022 Mar 2;28(3):364-372. doi: 10.1093/ibd/izab074.
Inflammatory bowel diseases (IBD) are rising in prevalence and are associated with high health care costs. We estimated trends in U.S. health care spending in patients with IBD between 1996 and 2016.
We used data on national health care spending developed by the Institute for Health Metrics and Evaluations for the Disease Expenditure Project. We estimated corresponding U.S. age-specific prevalence of IBD from the Global Burden of Diseases Study. From these 2 sources, we estimated prevalence-adjusted, temporal trends in U.S. health care spending in patients with IBD, stratified by age groups (<20 years, 20-44 years, 45-64 years, ≥65 years) and by type of care (ambulatory, inpatient, emergency department [ED], pharmaceutical prescriptions, and nursing care), using joinpoint regression, expressed as an annual percentage change (APC) with 95% confidence intervals.
Overall, annual U.S. health care spending on IBD increased from $6.4 billion (95% confidence interval, 5.7-7.4) in 1996 to $25.4 billion (95% confidence interval, 22.4-28.7) in 2016, corresponding to a per patient increase in annual spending from $5714 to $14,033. Substantial increases in per patient spending on IBD were observed in patients aged ≥45 years. Between 2011 and 2016, inpatient and ED care accounted for 55.8% of total spending and pharmaceuticals accounted for 19.9%, with variation across age groups (inpatient/ED vs pharmaceuticals: ages ≥65 years, 57.6% vs 11.2%; ages 45-64 years, 49.5% vs 26.9%; ages 20-44 years, 59.2% vs 23.6%).
Even after adjusting for rising prevalence, U.S. health care spending on IBD continues to progressively increase, primarily in middle-aged and older adults, with unplanned health care utilization accounting for the majority of costs.
炎症性肠病(IBD)的发病率正在上升,与高额的医疗保健费用有关。我们评估了 1996 年至 2016 年期间美国 IBD 患者的医疗保健支出趋势。
我们使用了 Institute for Health Metrics and Evaluations 为疾病支出项目开发的全国医疗保健支出数据。我们从全球疾病负担研究中估计了相应的美国年龄特异性 IBD 患病率。根据这两个来源,我们使用 Joinpoint 回归估计了 IBD 患者的患病率调整后的美国医疗保健支出趋势,按年龄组(<20 岁、20-44 岁、45-64 岁、≥65 岁)和护理类型(门诊、住院、急诊部门[ED]、处方药和护理)分层,以年度百分比变化(APC)表示,置信区间为 95%。
总体而言,1996 年美国 IBD 的年度医疗保健支出为 64 亿美元(95%置信区间,57-74),到 2016 年增加到 254 亿美元(95%置信区间,224-287),相应的每位患者的年度支出从 5714 美元增加到 14033 美元。≥45 岁的患者的 IBD 人均支出显著增加。在 2011 年至 2016 年期间,住院和 ED 护理占总支出的 55.8%,而药品占 19.9%,不同年龄组之间存在差异(住院/ED 与药品:年龄≥65 岁,57.6%与 11.2%;年龄 45-64 岁,49.5%与 26.9%;年龄 20-44 岁,59.2%与 23.6%)。
即使在调整了发病率上升的因素后,美国对 IBD 的医疗保健支出仍在持续增长,主要是在中年和老年人中,非计划性医疗保健利用占大部分成本。