Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Shaanxi, China.
Department of Spinal Surgery Hong-Hui Hospital Xi'an Jiaotong University.
Pain Physician. 2021 May;24(3):283-291.
Percutaneous kyphoplasty (PKP) has been reported to provide a favorable analgesic effect for pain caused by osteoporotic vertebral compression fractures (OVCFs). However, a systematic review demonstrated that pain relief was only reported for approximately 86% of kyphoplasty treatments.
To explore whether an additional facet joint block (FJB) can minimize pain and improve the clinical outcome of PKP in patients with acute OVCFs.
Prospective study.
All data were from Honghui Hospital in Xi'an.
According to the inclusion and exclusion criteria, 194 patients were eventually included in our study; they were randomly divided into 2 groups of 97 patients each and treated with either PKP + FJB or PKP alone. Follow-up consultations were scheduled 1 day, 3 days, 1 week, 1 month, 3 months, and 1 year postoperatively; the demographic characteristics, related surgical information, and complications observed within both groups were recorded. The clinical evaluation parameters included the intraoperative satisfaction score, the Visual Analog Scale (VAS) score, and the Oswestry Disability Index (ODI).
A total of 171 patients (61 men and 110 women; age range: 62-85 years) completed the full postoperative follow-up schedule, with 83 patients in the PKP + FJB group and 88 in the PKP group. No significant differences were observed in the genders, ages, preoperative bone mineral density, surgical levels, or volume of cement injected between the 2 groups (P > 0.05, respectively). The average duration of the surgeries in the PKP + FJB group was slightly longer than that in the PKP group (35.5 ± 4.8 min vs. 31.8 ± 4.3 min; P = 0.038), and in terms of the clinical outcomes, the average intraoperative satisfaction score was significantly higher in the PKP + FJB group (8.6 ± 1.1 vs. 6.3 ± 1.3; P < 0.001). Compared with the preoperative data, significant improvements in the VAS scores of back pain and ODI were observed at each follow-up interval (P < 0.05, respectively). These scores were significantly higher in the PKP + FJB group than in the PKP group; however, this was only observed within the first month after the procedure.
A single-center noncontrol study.
The addition of an FJB (which in our study involved a unique combination of ropivacaine, prednisolone, and vitamin B12) improved the short-term clinical outcome of PKP for acute OVCFs. The local anti-inflammatory and analgesic effects on the facet joints resulted in higher intraoperative satisfaction and lower VAS and ODI scores for the first postoperative month when compared with the PKP group.
经皮椎体后凸成形术(PKP)已被报道能为骨质疏松性椎体压缩性骨折(OVCFs)引起的疼痛提供良好的镇痛效果。然而,一项系统评价表明,仅约 86%的后凸成形术治疗报告了疼痛缓解。
探讨在急性 OVCFs 患者中,附加关节突关节阻滞(FJB)是否能最小化疼痛并改善 PKP 的临床结果。
前瞻性研究。
所有数据均来自西安红会医院。
根据纳入和排除标准,最终共有 194 例患者纳入本研究,他们被随机分为两组,每组 97 例,分别接受 PKP+FJB 或 PKP 单独治疗。术后 1 天、3 天、1 周、1 个月、3 个月和 1 年进行随访咨询,记录两组患者的人口统计学特征、相关手术信息和观察到的并发症。临床评估参数包括术中满意度评分、视觉模拟评分(VAS)和 Oswestry 功能障碍指数(ODI)。
共有 171 例患者(61 例男性和 110 例女性;年龄范围:62-85 岁)完成了完整的术后随访计划,其中 PKP+FJB 组 83 例,PKP 组 88 例。两组患者的性别、年龄、术前骨密度、手术节段或注入的水泥体积无显著差异(分别为 P>0.05)。PKP+FJB 组手术时间略长于 PKP 组(35.5±4.8 min 比 31.8±4.3 min;P=0.038),在临床结果方面,PKP+FJB 组的平均术中满意度评分明显更高(8.6±1.1 比 6.3±1.3;P<0.001)。与术前数据相比,两组患者在每个随访间隔的背痛 VAS 评分和 ODI 均有显著改善(分别为 P<0.05)。PKP+FJB 组的这些评分明显高于 PKP 组,但仅在术后 1 个月内观察到。
单中心非对照研究。
附加关节突关节阻滞(在我们的研究中,该阻滞采用罗哌卡因、泼尼松龙和维生素 B12 的独特组合)改善了急性 OVCFs 患者 PKP 的短期临床结果。关节突关节的局部抗炎和镇痛作用导致术后第一个月的术中满意度更高,VAS 和 ODI 评分更低,与 PKP 组相比。