Department of Nutrition and Food Hygiene, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
Department of Laboratory Detection, Taizhou Municipal Center for Disease Control and Prevention, Taizhou, Jiangsu, China.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021 Jul;38(7):1105-1117. doi: 10.1080/19440049.2021.1905883. Epub 2021 May 14.
The objective of this study was to measure the concentrations of three intensity sweeteners (Acesulfame-K, cyclamate and saccharin) in different categories of food available on the Nanjing market, and to investigate whether the Nanjing general population was at risk for exceeding the ADI of sweeteners. A set of 1885 foods was collected and analysed using the National Food Safety Standard procedure in order to establish the concentration levels of the sweeteners. Dietary exposure was estimated using probabilistic modelling software and compared directly with each sweetener's ADI. Consumption data from the China National Nutrition and Health Survey (conducted in 2010-2013) and the actual concentrations of sweeteners in the collected food products were used to perform the intake assessment. The results indicated that Acesulfame-K and cyclamate were commonly used in processed food, and processed nuts, preserved fruit, beverages, and bakery products are the main sources of sweeteners in Nanjing. The estimated exposure of sweeteners in Nanjing was well below the ADIs, as relative intakes at the 95th percentile were 29.7% for saccharin, 79.8% for cyclamate, and 35.9% for Acesulfame-K of the respective ADIs. It was concluded that adults were not at risk of exceeding ADIs for these sweeteners, but the intake of cyclamate at the higher percentiles by children may approach or slightly exceed ADI values.
本研究旨在测量三种强度甜味剂（乙酰磺胺酸钾、环己基氨基磺酸钠和糖精）在南京市场不同类别食品中的浓度，并调查南京普通人群是否有超过甜味剂每日允许摄入量（ADI）的风险。采用国家食品安全标准程序，对 1885 种食品进行了采集和分析，以确定甜味剂的浓度水平。使用概率建模软件估计了膳食暴露量，并将其与每种甜味剂的 ADI 直接进行了比较。消费数据来自中国国家营养与健康调查（2010-2013 年进行）和采集食品中实际的甜味剂浓度，用于进行摄入量评估。结果表明，乙酰磺胺酸钾和环己基氨基磺酸钠常用于加工食品，加工坚果、蜜饯水果、饮料和烘焙产品是南京甜味剂的主要来源。南京的甜味剂估计暴露量远低于 ADI，因为在第 95 百分位数处，糖精的相对摄入量为 ADI 的 29.7%，环己基氨基磺酸钠为 ADI 的 79.8%，乙酰磺胺酸钾为 ADI 的 35.9%。研究结论为，成年人摄入这些甜味剂不会超过 ADI，但儿童在较高百分位处摄入的环己基氨基磺酸钠可能接近或略超过 ADI 值。
