Almuhayawi Mohammed S, Al Jaouni Soad K, Almuhayawi Saad M, Selim Samy, Abdel-Mawgoud Mohamed
Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Hematology/Pediatric Oncology, Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Food Chem. 2021 Sep 30;357:129730. doi: 10.1016/j.foodchem.2021.129730. Epub 2021 Mar 31.
Sprouts have been regarded as a big store for bioactive compounds with a wide range of biological activities. Elevated CO (eCO, 620 μmol mol)was employed to enhance the nutritive and health promoting values of sprouts of two species of lemongrass, i.e. Cymbopogon citratus and Cymbopogon proximus. eCO improved the biomass production of sprouts, and their levels of primary metabolites e.g., amino acids and oils and active secondary metabolites e.g., phenolic compounds. As a result, eCO increased total antioxidant capacity, cytotoxicity against several human cancer cell lines, and antibacterial activities of Cymbopogon sprouts. We also recorded a significant increase in hypocholesterolaemic potential and anti-inflammatory activities of eCO-treated sprouts, as indicated by inhibition of cholesterol micellar solubility and pancreatic lipase activity, as well as lipoxygenase and cyclooxygenase activities, respectively. Thus, the present investigation supports the use of eCO as a promising approach to produce lemongrass sprouts with effective phytochemicals and enhanced biological activities.
芽苗菜被认为是生物活性化合物的重要储存库，具有广泛的生物活性。采用高浓度二氧化碳（eCO，620 μmol/mol）来提高两种柠檬草（即香茅和近缘香茅）芽苗菜的营养和促进健康价值。高浓度二氧化碳提高了芽苗菜的生物量产量，以及它们的初级代谢产物（如氨基酸和油脂）和活性次级代谢产物（如酚类化合物）的含量。结果，高浓度二氧化碳提高了香茅芽苗菜的总抗氧化能力、对几种人类癌细胞系的细胞毒性以及抗菌活性。我们还记录到，经高浓度二氧化碳处理的芽苗菜的降胆固醇潜力和抗炎活性显著增加，分别表现为对胆固醇胶束溶解度和胰脂肪酶活性以及脂氧合酶和环氧化酶活性的抑制。因此，本研究支持将高浓度二氧化碳作为一种有前景的方法，用于生产具有有效植物化学物质和增强生物活性的柠檬草芽苗菜。
