三氯乙酸（50%）治疗静脉性腿部溃疡。
Trichloroacetic acid (50%) in the treatment of venous leg ulcers.
机构信息
Department of dermatology and venerology, CHU Ibn Rochd, Casablanca, Morocco.
Department of dermatology and venerology, CHU Ibn Rochd, Casablanca, Morocco.
出版信息
J Med Vasc. 2021 May;46(3):139-143. doi: 10.1016/j.jdmv.2021.03.006. Epub 2021 Apr 8.
INTRODUCTION
Leg ulcers are a chronic and disabling condition that is difficult, time-consuming and costly to treat. We report a study evaluating the efficacy of trichloroacetic acid in the treatment of venous leg ulcers.
PATIENTS AND METHODS
We treated 19 patients with leg ulcers with 50% trichloroacetic acid with one application per week for 6 weeks. The primary evaluation criteria was healing, assessed by measuring the surface area of the ulcer before and after treatment.
RESULTS
We included 13 men and 6 women, with venous leg ulcers, with an average age of 57 years. The mean ulcer duration was 2.9 years. Complete healing was achieved in 2 patients, good healing in 9 patients, moderate healing in 6 patients, and poor healing in 2 patients.
DISCUSSION
Our study supports the data in the literature from two published series, and suggests that 50% trichloroacetic acid would be a good therapeutic alternative with satisfactory wound healing, low cost, and absence of adverse effects.
简介
腿部溃疡是一种慢性且使人丧失能力的疾病，治疗起来既困难又耗时，而且费用高昂。我们报告了一项评估三氯乙酸治疗静脉性腿部溃疡疗效的研究。
患者与方法
我们使用 50%的三氯乙酸为 19 例腿部溃疡患者进行每周一次的治疗，共进行 6 周。主要评估标准为愈合情况，通过测量治疗前后溃疡的表面积来评估。
结果
我们纳入了 13 名男性和 6 名女性患者，他们均患有静脉性腿部溃疡，平均年龄为 57 岁。溃疡平均持续时间为 2.9 年。2 例患者完全愈合，9 例患者愈合良好，6 例患者愈合中等，2 例患者愈合较差。
讨论
我们的研究支持了两篇已发表系列研究中的文献数据，表明 50%的三氯乙酸可能是一种很好的治疗选择，具有令人满意的伤口愈合效果、较低的成本，且无不良反应。
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