The Key Laboratory of Weak-Light Nonlinear Photonics, MOE, School of Physics and TEDA Applied Physics School, Nankai University, Tianjin, China.
The 2011 Project Collaborative Innovation Center for Biological Therapy, Nankai University, Tianjin, China.
J Biophotonics. 2021 Aug;14(8):e202100035. doi: 10.1002/jbio.202100035. Epub 2021 May 24.
As an important biomedical imaging method, endoscopic optical coherence tomography (OCT) is necessary to check its performance regularly. The ordinary plane phantoms are only able to evaluate part of image tangent to the probe. In this research, a spatial resolution estimate method of the endoscope OCT system is proposed. The annular phantom, made by uniformly distributing golden scattered microparticles in polydimethylsiloxane (PDMS), can provide dynamic scanning imaging evaluation of endoscopic OCT system, closer to its actual working status. The point spread function analysis method is used to analyze the imaging results of the annular phantom with the endoscopic OCT system. And many scattered particles are statistically analyzed to determine the spatial resolution of the endoscope OCT system. The method is low in cost, simple and convenient. It is valuable for the development of test standards for endoscope OCT systems.
作为一种重要的生物医学成像方法，内窥镜光学相干断层扫描（OCT）需要定期检查其性能。普通的平面体模只能评估与探头相切的部分图像。在这项研究中，提出了一种内窥镜 OCT 系统空间分辨率估计方法。该环形体模由均匀分布在聚二甲基硅氧烷（PDMS）中的金色散射微粒子制成，可提供内窥镜 OCT 系统的动态扫描成像评估，更接近其实际工作状态。采用点扩散函数分析方法对内窥镜 OCT 系统的环形体模成像结果进行分析。并对许多散射粒子进行统计分析，以确定内窥镜 OCT 系统的空间分辨率。该方法成本低、简单方便。它对内窥镜 OCT 系统测试标准的发展具有重要价值。
