Department of Health and Exercise Science, Appalachian State University, Boone, NC, USA.
Physiol Rep. 2021 May;9(9):e14852. doi: 10.14814/phy2.14852.
The aim of our study was to determine how being overweight (OW) affects measures of ejection duration (ED), subendocardial viability ratio (SEVR), and central arterial health in a sample of adolescent children. Thirty-four sex and age-matched adolescent children (n = 34, 17 OW, age = 14 ± 2 years) participated in one laboratory visit. Anthropometric measures, body composition, and cardiovascular measures including resting heart rate, aortic systolic blood pressure (ASBP), carotid-femoral pulse wave velocity (cf-PWV), ED (EDms absolute vs. relative ED%), and the SEVR were ascertained. Transfer functions were applied to obtain ASBP. ED was measured as the time from the beginning of the upstroke of the pulse wave and the dicrotic notch, SEVR as the quotient of the diastolic pressure-time area to the systolic pressure-time area, and cf-PWV as the quotient of distance between carotid-femoral measurement sites and the transit time of the pulse wave. cf-PWV was significantly higher in OW compared to normal weight participants (5.13 ± 0.85 vs. 4.53 ± 0.46 m/s respectively; p = 0.015, d = 0.51). OW adolescents also reported significantly higher values for ASBP (103.1 ± 11.8 vs. 95.7 ± 8.2 mmHg respectively; p = 0.043, d = 0.72) and significantly lower values of SEVR (114.4 ± 25.9% vs. 132.2 ± 22.0% respectively; p = 0.038; d = 0.33). Overweight adolescents demonstrated higher cf-PWV, ASBP, and SEVR then normal weight peers.
我们的研究目的是确定超重（OW）如何影响青少年样本中心射血时间（ED）、心内膜下活力比（SEVR）和中心动脉健康的测量值。34 名性别和年龄匹配的青少年儿童（n=34，17 名 OW，年龄=14±2 岁）参加了一次实验室访问。确定了人体测量学指标、身体成分和心血管指标，包括静息心率、主动脉收缩压（ASBP）、颈动脉-股动脉脉搏波速度（cf-PWV）、ED（EDms 绝对与相对 ED%）和 SEVR。应用传递函数获得 ASBP。ED 测量为脉搏波上升开始到二尖峰的时间，SEVR 为舒张压时间面积与收缩压时间面积的商，cf-PWV 为颈动脉-股动脉测量部位之间的距离与脉搏波传播时间的商。与正常体重参与者相比，OW 参与者的 cf-PWV 显著更高（分别为 5.13±0.85 和 4.53±0.46 m/s；p=0.015，d=0.51）。OW 青少年的 ASBP 也显著更高（分别为 103.1±11.8 和 95.7±8.2 mmHg；p=0.043，d=0.72），SEVR 显著更低（分别为 114.4±25.9%和 132.2±22.0%；p=0.038；d=0.33）。超重青少年的 cf-PWV、ASBP 和 SEVR 均高于正常体重同龄人。
