Department of Microbiology, Faculty of Medicine, Pelita Harapan University, Tangerang, Indonesia.
Department of Microbiology, Faculty of Medicine, Pelita Harapan University, Tangerang, Indonesia.
Int J Infect Dis. 2021 Jun;107:268-270. doi: 10.1016/j.ijid.2021.05.020. Epub 2021 May 13.
Healthcare workers (HCWs) are at increased risk of exposure to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), compared with the general population. Therefore, they are given priority for the COVID-19 vaccine in the national COVID-19 vaccination campaign in Indonesia. However, while the daily number of new COVID-19 cases remains high, and data regarding the efficacy of the vaccine in healthcare settings remain unavailable, vaccinated HCWs remain at risk of COVID-19 infection and further transmission.
To identify cases of COVID-19 among vaccinated HCWs at Siloam Teaching Hospital, Indonesia via active and passive surveillance conducted by the hospital's COVID-19 infection prevention and control unit.
Of 1040 HCWs who had received two doses of the COVID-19 vaccine, 13 (1.25%) tested positive for SARS-CoV-2 RNA on reverse transcriptase polymerase chain reaction between 2 and 11 days (median 5 days) after the second vaccination.
Laboratory-confirmed COVID-19 among vaccinated HCWs soon after the second vaccination indicates that HCWs remain at risk of COVID-19. Therefore, the presence of symptoms soon after full vaccination cannot be considered as vaccine-related symptoms, and regular COVID-19 testing should be conducted among HCWs.
与一般人群相比,医护人员(HCWs)接触严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的风险增加,SARS-CoV-2 是导致 2019 年冠状病毒病(COVID-19)的原因。因此,他们在印度尼西亚全国 COVID-19 疫苗接种活动中被优先接种 COVID-19 疫苗。然而,尽管每日新增 COVID-19 病例数仍然很高,而且关于疫苗在医疗保健环境中的功效的数据仍然不可用,但接种疫苗的 HCWs 仍有感染 COVID-19 并进一步传播的风险。
通过 Siloam 教学医院 COVID-19 感染预防和控制部门进行的主动和被动监测,在印度尼西亚 Siloam 教学医院识别接种疫苗的 HCWs 中 COVID-19 病例。
在接种了两剂 COVID-19 疫苗的 1040 名 HCWs 中,有 13 名(1.25%)在第二次接种后 2 至 11 天(中位数 5 天)内通过逆转录聚合酶链反应检测到 SARS-CoV-2 RNA 呈阳性。
在第二次接种后不久,接种疫苗的 HCWs 中实验室确诊的 COVID-19 表明 HCWs 仍有感染 COVID-19 的风险。因此,完全接种疫苗后出现症状不能被认为是与疫苗相关的症状,应该对 HCWs 进行定期 COVID-19 检测。