Ali Syed Amaan, Bhattacharyya Shyamalima, Ahmad Faisal Noor, Tiwari Rahul V C, Jain Teerthesh, Baad Shrusti Rajendra, Tiwari Heena Dixit
Department of Periodontics and Community Dentistry, Dr. Ziauddin Ahmed Dental College and Hospital, Aligarh Muslim University, Aligarh, UP, India.
Department of Public Health Dentistry, Government Dental College, Dibrugarh, Assam, India.
J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S196-S199. doi: 10.4103/jpbs.jpbs_132_22. Epub 2022 Jul 13.
Many new variants of the coronavirus are infecting the already vaccinated people. There have been reports of deaths also among the already vaccinated subjects. Hence, we conducted a systematic review and meta-analysis of the infection breakthrough after COVID vaccination.
We piloted a review of the healthcare workers who completed the vaccination for COVID. The data were collected from the online resources for the breakthrough infections after vaccination. We then enumerated those subjects who had a breakthrough infection post-vaccination. The data collected were meta-analyzed for the incidence of the infection among the vaccinated individuals.
We observed that among nearly 2.3 lakh subjects, less than 3% were infected with the various new strains of the virus. The ratio of the breakthrough infection was different for the vaccinated (1.2%) and the partially vaccinated (3.2%) individuals with greater infection among the partially infected individuals.
The breakthrough infections are very low among vaccinated individuals and even lower among fully vaccinated individuals. Hence, vaccination is highly recommended to prevent the loss of life.
许多新冠病毒新变种正在感染已接种疫苗的人群。已有报告称，在已接种疫苗的人群中也出现了死亡病例。因此，我们对新冠疫苗接种后的突破性感染进行了系统评价和荟萃分析。
我们对完成新冠疫苗接种的医护人员进行了一项综述。数据从在线资源中收集，内容为接种疫苗后的突破性感染情况。然后，我们统计了那些接种疫苗后出现突破性感染的受试者。对收集到的数据进行荟萃分析，以得出接种疫苗个体的感染发生率。
我们观察到，在近23万名受试者中，感染各种新毒株的比例不到3%。突破性感染率在已接种疫苗者（1.2%）和部分接种疫苗者（3.2%）中有所不同，部分接种疫苗者的感染情况更为严重。
突破性感染在接种疫苗的个体中非常低，在完全接种疫苗的个体中更低。因此，强烈建议接种疫苗以防止生命损失。
