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艾滋病毒感染者接种首剂严重急性呼吸综合征冠状病毒 2 信使 RNA 疫苗的安全性和抗体反应。

Safety and antibody response to the first dose of severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine in persons with HIV.

机构信息

Department of Surgery.

Division of Infectious Diseases, Department of Medicine.

出版信息

AIDS. 2021 Sep 1;35(11):1872-1874. doi: 10.1097/QAD.0000000000002945.

DOI:10.1097/QAD.0000000000002945
PMID:33993131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10323866/
Abstract

In this study of 12 people with HIV (PWH) who received the first dose of SARS-CoV-2 mRNA vaccination, anti-SARS-CoV-2 receptor-binding domain antibodies were detectable in all participants; lower antibody levels were seen in those with lower CD4+ counts, and vaccine reactions were generally mild.

摘要

在这项研究中，12 名 HIV 感染者（PWH）接种了第一剂 SARS-CoV-2 mRNA 疫苗，所有参与者均可检测到抗 SARS-CoV-2 受体结合域抗体；CD4+计数较低者的抗体水平较低，疫苗反应通常较轻。

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