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[对比剂所致急性肾损伤]

[Contrast-induced acute kidney injury].

作者信息

Pillebout Évangeline, Martinez Frank

机构信息

Service de néphrologie-transplantation, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.

Service de transplantation, hôpital Necker, 149, rue de Sèvre, 75015 Paris, France.

出版信息

Nephrol Ther. 2021 Jun;17(3):191-198. doi: 10.1016/j.nephro.2021.04.001. Epub 2021 May 11.

Abstract

The nephrotoxicity of iodinated contrast agent/media is defined by acute renal failure occurring within 48 to 72 hours after injection of iodized contrast product, in the absence of other etiology. The risk factors for contrast agent renal injury must systematically be sought before the exam. The presence of risk factors, including the existence of a renal failure defined by a creatinine clearance (eGFR) of less than 60 mL/min/1.73 m, requires to take prevention measures including hydration. If eGFR is less than 30 mL/min/1.73 m, the advice of a nephrologist is necessary.

摘要

碘化造影剂/介质的肾毒性定义为在注射碘化造影剂后48至72小时内发生的急性肾衰竭,且不存在其他病因。在检查前必须系统地寻找造影剂肾损伤的危险因素。存在危险因素,包括肌酐清除率(估算肾小球滤过率)低于60 mL/min/1.73 m²所定义的肾衰竭,需要采取包括水化在内的预防措施。如果估算肾小球滤过率低于30 mL/min/1.73 m²,则需要肾病科医生的建议。

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