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在使用 Impella 5.0 设备的晚期心力衰竭患者中,进行神经肌肉电刺激和活动治疗期间的血液动力学变化。

Hemodynamic Changes During Neuromuscular Electrical Stimulation and Mobility Therapy for an Advanced Heart Failure Patient with Impella 5.0 Device.

机构信息

Department of Rehabilitation, Kitasato University Hospital.

Department of Cardiovascular Medicine, Kitasato University School of Medicine.

出版信息

Int Heart J. 2021 May 29;62(3):695-699. doi: 10.1536/ihj.20-632. Epub 2021 May 15.

Abstract

The Impella 5.0 is a catheter-mounted left ventricular assist device that is inserted through the patient's subclavian artery. This device allows patient mobilization. Early mobility improves outcomes, including physical function and exercise tolerance, in critically ill patients and those with heart failure (HF). However, there have been no studies regarding the safety of early mobilization during the period of Impella 5.0 insertion based on hemodynamic assessment.A 39-year-old man with idiopathic dilated cardiomyopathy and cardiogenic shock was transferred to our hospital for Impella 5.0 insertion. We started neuromuscular electrical stimulation (NMES) and mobilization eight days after Impella 5.0 insertion. The safety of NMES and mobilization was assessed based on mean blood pressure, heart rate (HR), and mean pulmonary artery pressure measurements as hemodynamic indicators. Muscle strength was also assessed using the Medical Research Council (MRC) scale. Throughout the interventions, only the HR increased slightly during mobilization, and there were no hemodynamic abnormalities. Also, the MRC scale score improved as mobilization progressed. The results presented here suggest that NMES and mobilization are safe and feasible in patients with Impella 5.0 insertion, and therefore should be widely adopted.

摘要

Impella 5.0 是一种经皮插入患者锁骨下动脉的左心室辅助装置。该装置可实现患者的活动能力。对于危重症患者和心力衰竭(HF)患者,早期活动可改善预后,包括身体机能和运动耐量。然而,目前还没有基于血流动力学评估的关于 Impella 5.0 插入期间早期活动安全性的研究。

一名 39 岁男性,患有特发性扩张型心肌病和心源性休克,转入我院进行 Impella 5.0 插入。我们在插入 Impella 5.0 八天后开始进行神经肌肉电刺激(NMES)和活动。根据平均血压、心率(HR)和平均肺动脉压测量值作为血流动力学指标,评估 NMES 和活动的安全性。还使用医疗研究委员会(MRC)量表评估肌肉力量。在整个干预过程中,只有在活动时 HR 略有升高,没有出现血流动力学异常。此外,随着活动的进行,MRC 量表评分也有所提高。

这些结果表明,在 Impella 5.0 插入的患者中,NMES 和活动是安全且可行的,因此应该广泛采用。

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