Silva Almodóvar Armando, Nahata Milap C
College of Pharmacy, The Ohio State University, Columbus, OH, United States.
SinfoniaRx: A TRHC Solution, Tucson, AZ, United States.
Front Pharmacol. 2021 Apr 30;12:612941. doi: 10.3389/fphar.2021.612941. eCollection 2021.
Heart failure (HF) is associated with significant morbidity, mortality, compromised quality of life and socioeconomic burden worldwide. This chronic condition is becoming an increasingly important concern given the increased prevalence of HF among aging populations. Significant contributors toward escalating health care costs are emergency room visits and hospitalizations associated with HF. An important strategy to improve health care outcomes and reduce unnecessary costs is to identify and reduce the prescribing of potentially harmful medications (PHMs) among adults with HF. Previous studies in patients with HF found roughly 10-50% of them were prescribed at least one PHM in ambulatory care and inpatient health care settings. This opinion highlights recent findings from studies assessing prevalence of PHMs, associations between PHM prescribing and characteristics, and what can be done to improve patient outcomes and reduce the use of PHMs and associated health care costs in adults with HF.
心力衰竭（HF）在全球范围内与显著的发病率、死亡率、生活质量受损以及社会经济负担相关。鉴于HF在老年人群中的患病率不断上升，这种慢性疾病正日益成为一个重要的关注点。导致医疗保健成本不断攀升的一个重要因素是与HF相关的急诊室就诊和住院治疗。改善医疗保健结果并降低不必要成本的一项重要策略是识别并减少HF成年患者中潜在有害药物（PHM）的处方。先前针对HF患者的研究发现，在门诊护理和住院医疗环境中，约10%至50%的患者至少被开具了一种PHM。本观点强调了近期研究的结果，这些研究评估了PHM的患病率、PHM处方与特征之间的关联，以及为改善HF成年患者的预后、减少PHM的使用及相关医疗保健成本可采取的措施。
