Baker T J, Gordon H L
Plast Reconstr Surg. 1988 Aug;82(2):244-6. doi: 10.1097/00006534-198808000-00005.
Midazolam is a very useful drug in outpatient aesthetic surgery. Its principal advantages are (1) short duration of action (a half-life of 2.3 hours), (2) painless injection, (3) no incidence of postoperative phlebitis (as compared with diazepam), and (4) a high degree of safety and effectiveness. Since one of the main objectives in outpatient surgery is to have the patient recover as quickly as possible and be discharged without any significant drug hangover, we recommend the incorporation of midazolam into the armamentarium of the aesthetic surgeon. Subsequent to the presentation of this paper (Twentieth Annual Meeting of the American Society for Aesthetic Plastic Surgery, in Los Angeles, California, March 23, 1987), we have administered midazolam to an additional 400 patients undergoing outpatient surgery and no apnea has occurred requiring an airway or supportive respiratory measures.
咪达唑仑在门诊美容手术中是一种非常有用的药物。其主要优点包括:(1)作用持续时间短(半衰期为2.3小时);(2)注射无痛;(3)术后静脉炎发生率低(与地西泮相比);(4)高度安全有效。由于门诊手术的主要目标之一是让患者尽快康复并在无明显药物残留的情况下出院,我们建议美容外科医生将咪达唑仑纳入其常用药物中。在本文发表之后(1987年3月23日于加利福尼亚州洛杉矶举行的美国美容整形外科学会第二十届年会),我们又对另外400例接受门诊手术的患者使用了咪达唑仑,未发生需要气道或支持性呼吸措施的呼吸暂停情况。