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真实世界临床实践中血脂异常的管理:VIPFARMA ISCP项目的基本原理与设计

Management of Dyslipidaemia in Real-world Clinical Practice: Rationale and Design of the VIPFARMA ISCP Project.

作者信息

Santi Ricardo Lopez, Martinez Felipe, Baranchuk Adrian, Liprandi Alvaro Sosa, Piskorz Daniel, Lorenzatti Alberto, Santi Maria Pilar Lopez, Kaski Juan Carlos

机构信息

Division of Cardiology, Hospital Italiano de La Argentina La Plata, Buenos Aires, Argentina.

Instituto Médico DAMIC-Fundacion Rusculleda Cordoba, Argentina.

出版信息

Eur Cardiol. 2021 Apr 27;16:e16. doi: 10.15420/ecr.2020.42. eCollection 2021 Feb.

Abstract

Dyslipidaemia plays a major role in the pathogenesis of atherosclerosis. Every year, scientific institutions publish cardiovascular prevention guidelines with updated goals and recommendations based on new evidence. However, medical barriers exist that make achieving these goals difficult and gaps between guidelines and best daily clinical practice still persist. The International Society of Cardiovascular Pharmacotherapy designed the Surveillance of Prescription Drugs in the Real World Project (VIPFARMA ISCP), a survey for physicians who manage lipid disorders in high-risk patients. Seven clusters of questions will be analysed comprising demographics, institution profile, access to continuing medical education, clinical practice profile, attitude regarding use of statins, knowledge regarding proprotein convertase subtilisin/kexin type 9 inhibitors and attitudes regarding medical decisions about triglycerides. The present study will be the first part of a larger programme and aims to shed light on barriers between lipid-lowering drug therapy recommendations in the 2019 European Society of Cardiology guidelines and clinical practice in different countries.

摘要

血脂异常在动脉粥样硬化的发病机制中起主要作用。每年,科研机构都会根据新证据发布心血管疾病预防指南,更新目标和建议。然而,存在一些医学障碍使得实现这些目标变得困难,而且指南与日常最佳临床实践之间的差距仍然存在。国际心血管药物治疗学会设计了“现实世界项目中处方药监测”(VIPFARMA ISCP),这是一项针对管理高危患者血脂异常的医生的调查。将分析七组问题,包括人口统计学、机构概况、继续医学教育的获取情况、临床实践概况、对他汀类药物使用的态度、对前蛋白转化酶枯草溶菌素/kexin 9型抑制剂的了解以及对甘油三酯医疗决策的态度。本研究将作为一个更大项目的第一部分,旨在阐明2019年欧洲心脏病学会指南中降脂药物治疗建议与不同国家临床实践之间的障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74ad/8117136/b7e067d141b8/ecr-16-e16-g001.jpg

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