[治疗效益因子对快中子剂量的依赖性]
[Dependence of the therapeutic benefit factor on the dose of fast neutrons].
作者信息
Lisin V A
出版信息
Radiobiologiia. 1988 May-Jun;28(3):343-6.
PMID:3399634
Abstract
An analytical equation was obtained to describe the therapeutic effectiveness factor (TEF) as a function of radiation dose. By this equation TEF function of dose was found for rhabdomyosarcoma that showed a considerable dependence of TEF upon dose fractionation schedule. At the same time, TEF gave no unique information on the advantage of neutron therapy since doses at which TEF was maximum did not correspond to those providing the highest effectiveness of the treatment.
摘要
得到了一个解析方程，用于描述作为辐射剂量函数的治疗效果因子（TEF）。通过该方程，发现了横纹肌肉瘤的剂量TEF函数，结果表明TEF对剂量分割方案有相当大的依赖性。同时，TEF并未提供关于中子治疗优势的独特信息，因为TEF最大值对应的剂量与提供最高治疗效果的剂量并不一致。
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