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采用“观察等待”方案的直肠癌患者发生乙状结肠急性缺血性坏疽

Acute Ischemic Gangrene of the Rectosigmoid Colon in a Patient With Rectal Cancer in the "Watch-and-Wait" Protocol.

作者信息

Aliyev Vusal, Goksel Suha, Asoglu Oktar

机构信息

General and Colorectal Surgery, Maslak Acibadem Hospital, Istanbul, TUR.

Pathology, Maslak Acibadem Hospital, Istanbul, TUR.

出版信息

Cureus. 2021 May 13;13(5):e14998. doi: 10.7759/cureus.14998.

DOI:10.7759/cureus.14998
PMID:33996340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8117261/
Abstract

Acute rectal ischemia is a rare entity because the rectum has abundant blood supply from the inferior mesenteric, internal iliac, internal pudendal, and marginal artery with rich collaterals. We present a case of an acute ischemic proctosigmoiditis with a history of rectal cancer who completely recovered after total neoadjuvant treatment and was in the "watch-and-wait" protocol. Urgent laparoscopic low anterior resection and protective ileostomy were performed. Causes of acute rectosigmoid ischemia include old age, diabetes, atherosclerosis, previous aortic surgery due to aneurysm, vasculitis, and radiotherapy. Ischemia may be present as only involving the mucosa, which can be managed conservatively, but full-thickness necrosis requires urgent surgical intervention. Endoscopic examination is the gold standard in initial diagnosis. Ischemic gangrene of the rectosigmoid colon is a rare condition and can be life-threatening unless an urgent surgical intervention is performed.

摘要

急性直肠缺血是一种罕见的病症,因为直肠有丰富的血液供应,来自肠系膜下动脉、髂内动脉、阴部内动脉以及具有丰富侧支循环的边缘动脉。我们报告一例急性缺血性直肠乙状结肠炎病例,患者有直肠癌病史,在接受全新辅助治疗后完全康复,并采用“观察等待”方案。实施了紧急腹腔镜低位前切除术和保护性回肠造口术。急性直肠乙状结肠缺血的病因包括老年、糖尿病、动脉粥样硬化、既往因动脉瘤进行的主动脉手术、血管炎和放疗。缺血可能仅累及黏膜,这种情况可保守处理,但全层坏死则需要紧急手术干预。内镜检查是初步诊断的金标准。直肠乙状结肠的缺血性坏疽是一种罕见病症,除非进行紧急手术干预,否则可能危及生命。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/8e0b02c5afc0/cureus-0013-00000014998-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/a8bba4de2da6/cureus-0013-00000014998-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/b5c400f32d4b/cureus-0013-00000014998-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/55d76ba08f0e/cureus-0013-00000014998-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/9cbba21e36c6/cureus-0013-00000014998-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/358b20f3be83/cureus-0013-00000014998-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/c7958a23c7e1/cureus-0013-00000014998-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/8e0b02c5afc0/cureus-0013-00000014998-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/a8bba4de2da6/cureus-0013-00000014998-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/b5c400f32d4b/cureus-0013-00000014998-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/55d76ba08f0e/cureus-0013-00000014998-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/9cbba21e36c6/cureus-0013-00000014998-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/358b20f3be83/cureus-0013-00000014998-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/c7958a23c7e1/cureus-0013-00000014998-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/112c/8117261/8e0b02c5afc0/cureus-0013-00000014998-i07.jpg

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Phase II, randomized study of concomitant chemoradiotherapy followed by surgery and adjuvant capecitabine plus oxaliplatin (CAPOX) compared with induction CAPOX followed by concomitant chemoradiotherapy and surgery in magnetic resonance imaging-defined, locally advanced rectal cancer: Grupo cancer de recto 3 study.磁共振成像定义的局部进展期直肠癌的同期放化疗后手术和辅助卡培他滨加奥沙利铂(CAPOX)与诱导 CAPOX 后同期放化疗和手术的随机 II 期研究:Grupo cancer de recto 3 研究。
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