Latief Muzamil, Shafi Obeid, Hassan Zhahid, Farooq Summyia, Abbas Farhat
Nephrology Division, GMC Secunderabad, Hyderabad.
Flushing Hospital, Medical Center, New York, USA.
Med J Islam Repub Iran. 2021 Feb 3;35:17. doi: 10.47176/mjiri.35.17. eCollection 2021.
COVID-19 is a novel highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Immunosuppressed people are at a higher risk for unfavourable outcomes if infected with SARS-CoV-2, as cellular immunity plays a key role in determining the course and outcome in COVID-19. Kidney transplant recipients (KTRs) are thus a distinct subset of the population. We describe our early experience with 2 KTRs requiring hospital admission due to COVID-19 and who recovered well. We conclude that timely intervention in the form of modifying immunosuppression and close monitoring and institution of further measures based on clinical severity is needed in KTRs with COVID-19.
2019冠状病毒病（COVID-19）是一种由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的新型高传染性疾病。免疫抑制人群感染SARS-CoV-2后出现不良后果的风险更高，因为细胞免疫在决定COVID-19的病程和结局中起关键作用。肾移植受者（KTRs）因此属于这一特殊人群。我们描述了2例因COVID-19需要住院治疗且恢复良好的KTRs的早期经验。我们得出结论，对于感染COVID-19的KTRs，需要及时采取调整免疫抑制的干预措施，并根据临床严重程度进行密切监测和采取进一步措施。
