[Enterotoxic activity of live cultures of Sonne dysentery microbes and formation of enterotoxin in vivo].

The great majority of virulent Sonne dysentery bacillus cultures caused an accumulation of the fluid in the lumen of the isolated segment of the rabbit small intestine containing a great amount of mucus and sometimes of the blood as well; the segment mucosa was hyperemic and had punctate hemorrhages. Avirulent microbial cultures as a rule caused no exudation in the intestinal lumen. Sterile and concentrated contents of the intestinal loops responding to the centrated contents of the intestinal loops responding to the administration of the virulent culture of Sonne bacillus or a toxigenic strain of Grigoriev-Shiga dysentery bacillus caused a positive response in other rabbits. The character of the exudate and the changes in the mucosa failed to differ from such following the administration of live cultures.