COVID-19 相关静脉血栓栓塞症的临床-放射学相关性：多学科研究的初步结果。
Clinical-radiological correlations in COVID-19-related venous thromboembolism: Preliminary results from a multidisciplinary study.
机构信息
Division of Internal Medicine, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Division of Anesthesiology and Intensive Care, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy.
出版信息
Int J Clin Pract. 2021 Sep;75(9):e14370. doi: 10.1111/ijcp.14370. Epub 2021 May 29.
INTRODUCTION
Among the multiple complex pathophysiological mechanisms underlying COVID-19 pneumonia, immunothrombosis has been shown to play a key role. One of the most dangerous consequences of the prothrombotic imbalance is the increased incidence of micro- and macrothrombotic phenomena, especially deep vein thrombosis (DVT) and pulmonary embolism (PE).
METHODS
We investigated the correlation between radiological and clinical-biochemical characteristics in a cohort of hospitalised COVID-19 patients.
RESULTS
PE was confirmed in 14/61 (23%) patients, five (35.7%) had DVT. The radiographic findings, quantified by Qanadli score calculated on CT angiography, correlated with the clinical score and biochemical markers. The ratio between the right and left ventricle diameter measured at CT angiography correlated with the length of hospital stay.
CONCLUSION
In our cohort radiological parameters showed a significant correlation with clinical prognostic indices and scores, thus suggesting that a multidisciplinary approach is advisable in the evaluation of PE in COVID-19 patients.
简介
在导致 COVID-19 肺炎的多种复杂病理生理机制中，免疫血栓形成被证明起着关键作用。促凝失衡最危险的后果之一是微血栓和大血栓现象的发生率增加，特别是深静脉血栓形成（DVT）和肺栓塞（PE）。
方法
我们调查了住院 COVID-19 患者队列中放射学和临床生物化学特征之间的相关性。
结果
14/61（23%）的患者证实有 PE，5 例（35.7%）有 DVT。通过 CT 血管造影计算的 Qanadli 评分定量的影像学发现与临床评分和生化标志物相关。CT 血管造影测量的右心室和左心室直径比值与住院时间相关。
结论
在我们的队列中，放射学参数与临床预后指数和评分有显著相关性，因此建议对 COVID-19 患者的 PE 进行多学科评估。
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