Mikowski Mia, Evans Teodoro, Wu Lihteh
Asociados de Macula, Vitreo y Retina de Costa Rica, San José, Costa Rica.
Vitreoretinal Department, Clinica 2020, San José, Costa Rica.
Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1964-1969. doi: 10.1080/09273948.2021.1906912. Epub 2021 May 17.
To report two cases of acute syphilitic posterior placoid chorioretinitis (ASPPC) with choriocapillaris flow voids that partially resolved with systemic antibiotic treatment.
Observational case report with multimodal imaging.
Two young healthy men suffered an acute monocular loss of vision. Spectral domain optical coherence tomography (SD-OCT) and OCT angiography (OCT-A) revealed outer retinitis with loss of the ellipsoid layer and choriocapillaris flow voids. Systemic work-up revealed syphilis. Upon systemic treatment with antibiotics, the patients recovered their vision and the OCT and OCT-A abnormalities partially resolved.
Transient choriocapillaris flow voids characterize ASPPC and may be responsible for the visual loss seen in these patients.
报告两例急性梅毒性后极部扁平状脉络膜视网膜炎（ASPPC）伴有脉络膜毛细血管血流缺失，经全身抗生素治疗后部分症状缓解。
采用多模态成像的观察性病例报告。
两名年轻健康男性出现急性单眼视力丧失。频域光学相干断层扫描（SD-OCT）和光学相干断层扫描血管造影（OCT-A）显示外层视网膜病变，伴有椭圆体层缺失和脉络膜毛细血管血流缺失。全身检查发现梅毒。经抗生素全身治疗后，患者视力恢复，OCT和OCT-A异常部分缓解。
短暂性脉络膜毛细血管血流缺失是ASPPC的特征，可能是这些患者视力丧失的原因。
